1352152-41-0

Usage

Chemical structure

A heterocyclic compound with a dihydropyridin-2-one core and a difluoromethyl and dioxaborolan-2-yl substituent.

Application

Commonly used in pharmaceutical research and drug development.

Potential applications

Synthesis of various bioactive molecules and drug candidates.

Suitability

Suitable for use as a building block in organic synthesis, medicinal chemistry, and drug discovery.

Unique structure

The compound has a unique structure that contributes to its reactivity and potential applications.

Reactivity

The compound's unique structure and reactivity make it a valuable tool for the development of new drugs and therapeutic agents.

Development

The compound has potential for use in the development of new drugs and therapeutic agents due to its unique structure and reactivity.

Research

The compound is of interest to researchers in the fields of pharmaceutical research and drug development.

Synthesis

The compound can be synthesized and used in the synthesis of various bioactive molecules and drug candidates.

Properties

The compound possesses interesting properties that make it suitable for use in organic synthesis, medicinal chemistry, and drug discovery.

Upstream product

• 899452-27-8 N-[5-bromo-1-(difluoromethyl)pyridin-2(1H)-ylidene]acetamide 
• 1198765-29-5 N-[(2E)-5-bromo-1-(difluoromethyl)pyridin-2(1H)-ylidene]acetamide 
• 7169-97-3 N-(5-bromopyridin-2-yl)acetamide 
• 832735-61-2 5-bromo-1-(difluoromethyl)-1,2-dihydropyridin-2-one 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1352152-43-2 (S)-tert-butyl 1-(1-cyano-2-(4-(1-(difluoromethyl)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethylcarbamoyl)cyclohexylcarbamate 
• 1352152-40-9 (S)-1-amino-N-(1-cyano-2-(4-(1-(difluoromethyl)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethyl)cyclohexanecarboxamide 
• 1352152-42-1 (S)-tert-butyl 1-(1-amino-3-(4-(1-(difluoromethyl)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)cyclohexylcarbamate 

Relevant academic research and scientific papers

SUBSTITUTED 2-AMINO-PYRAZOLYL-[1,2,4]TRIAZOLO[1,5A] PYRIDINE DERIVATIVES AND USE THEREOF

Provided herein are 2-amino-pyrazolyl-[ 1,2,4]triazolo [1,5a]pyridine derivatives. Such compounds are useful, for example, for the treatment and/or prevention of neurodegenerative diseases or disorders such as ophthalmological neurodegenerative disorders. This disclosure also features compositions containing the same as well as methods of using and making the same.

PYRAZINE COMPOUNDS AND USES THEREOF

The present disclosure novel pyrazine compounds targeting adenosine receptors (especially A1 and A2, particularly A2a). The present disclosure also relates to pharmaceutical compositions comprising one or more of the compounds as an active ingredient, and use of the compounds in the treatment of adenosine receptor (AR) associated diseases, for example cancer such as NSCLC, RCC, prostate cancer, and breast cancer.

Substituted thiazole derivative and application thereof

The invention provides a compound represented by a general formula (I), or a stereoisomer, pharmaceutically acceptable salt, solvate, hydrate, chemically protective form or prodrug thereof. The compound has an effect of inhibiting adenosine receptor 2a (A2a), and can be used as an antagonist of the adenosine receptor 2a (A2A) for treating tumors.

PYRROLOPYRIDAZINE JAK3 INHIBITORS AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.

SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760

The present invention provides compounds of formula (I) in which, n, R1, R2 and Q are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.