1352240-48-2

Upstream product

• 823-85-8 4-fluorophenyhydrazine hydrochloride 
• 1352240-47-1 5-fluoro-2-{2-[(4aS,5S,7S)-1-(4-fluorophenyl)-5,7-dihydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethyl}benzamide 
• 1021539-02-5 MK-5932 
• 1021539-51-4 5-fluoro-2-{2-[(4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethyl}benzoic acid 
• 1021539-50-3 methyl 5-fluoro-2-{2-[(4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethyl}benzoate 
• 1021539-49-0 methyl 5-fluoro-2-{[(4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethynyl}benzoate 
• 754235-83-1 (4aS,5R)-5-ethynyl-1-(4-fluorophenyl)-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol 

Downstream Products

• 1352240-45-9 5-fluoro-2-{2-[(4aS,5S,7R)-1-(4-fluorophenyl)-5,7-dihydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethyl}benzamide 

Relevant academic research and scientific papers

Discovery of selective glucocorticoid receptor modulator MK-5932

A series of partial agonists of the Glucocorticoid Receptor were prepared targeting reduced transactivation activity, while maintaining significant transrepression activity. Incorporation of an ortho-aryl amide produced compounds with the desired in vitro