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1352435-37-0

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1352435-37-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1352435-37-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,2,4,3 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1352435-37:
(9*1)+(8*3)+(7*5)+(6*2)+(5*4)+(4*3)+(3*5)+(2*3)+(1*7)=140
140 % 10 = 0
So 1352435-37-0 is a valid CAS Registry Number.

1352435-37-0Downstream Products

1352435-37-0Relevant articles and documents

Synthesis and antitumor efficacy of a β-glucuronidase-responsive albumin-binding prodrug of doxorubicin

Legigan, Thibaut,Clarhaut, Jonathan,Renoux, Brigitte,Tranoy-Opalinski, Isabelle,Monvoisin, Arnaud,Berjeaud, Jean-Marc,Guilhot, Fran?ois,Papot, Sébastien

, p. 4516 - 4520 (2012/08/13)

In this paper we describe the synthesis and biological evaluation of the first β-glucuronidase-responsive albumin-binding prodrug designed for the selective delivery of doxorubicin at the tumor site. This prodrug leads to superior antitumor efficacy in mice compared to HMR 1826, a well-known glucuronide prodrug of doxorubicin that cannot bind covalently to circulating albumin. Furthermore, this compound inhibits tumor growth in a manner similar to that of doxorubicin while avoiding side effects induced by the free drug.

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