135263-84-2

Basic information

• Product Name: (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (2S)-2-<(tert-butoxycarbonyl)amino>pent-4-enoate
• Synonyms: (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (2S)-2-<(tert-butoxycarbonyl)amino>pent-4-enoate
• CAS NO: 135263-84-2
• Molecular Weight: 429.6
• Mol File: 135263-84-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (2S)-2-<(tert-butoxycarbonyl)amino>pent-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (2S)-2-<(tert-butoxycarbonyl)amino>pent-4-enoate(135263-84-2)
• EPA Substance Registry System: (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (2S)-2-<(tert-butoxycarbonyl)amino>pent-4-enoate(135263-84-2)

Safety Data

• Hazardous Substances Data: 135263-84-2(Hazardous Substances Data)

Upstream product

• 117681-86-4 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (tert-butoxycarbonyl)aminoacetate 
• 65253-04-5 (-)-8-phenylmenthol 
• 4530-20-5 BOC-glycine 
• 24850-33-7 allyltributylstanane 
• 117049-08-8 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl<(tert-butoxycarbonyl)amino>bromoacetate 
• 1730-25-2 allylmagnesium bromide 
• 117049-09-9 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (S)-2-<(tert-butoxycarbonyl)amino>bromoacetate 
• 119479-32-2 2-((tert-butyloxycarbonyl)amino)-4-pentenoic acid 

Downstream Products

• 135263-89-7 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (S)-2-<(tert-butoxycarbonyl)amino>pentanoate 
• 54594-06-8 D-allylglycine 
• 16338-48-0 L-allylglycine 
• 3209-39-0 2-amino-4-hydroxypentanoic acid 

Relevant articles and documents

Asymmetric Induction in Acyclic Radical Reactions: Enantioselective Syntheses of α-Amino Acids via Carbon-Carbon Bond Forming Radical Reactions.

The derivative of glycine, 8-phenylmenthyl N-Boc-2-bromoglycinate 1 reacted with allyltri-n-butylstannanes via the corresponding radical 2 by the SH2' mechanism to give (2S) allyl amino acid derivatives with high diastereoselectivity.The reaction of 1 with triphenyl(1,2-propadienyl)stannane and triphenyl(2-propynyl)stannane gave the (2S) allenyl and (2S) propargyl amino acid derivatives respectively also with high diastereoselectivity but by a different mechanism.

Enantioselective Syntheses of α-Amino Acids via Carbon-Carbon Bond Forming Radical Reactions

The derivative of glycine, 8-phenylmenthyl N-Boc-2-bromoglycinate 2 reacts with unsaturated stannanes to give unsaturated amino acid derivatives with high diastereoselectivity.