135273-33-5Relevant academic research and scientific papers
New experiments in the reductive N-alkylation and N-peralkylation of aromatic amines
Verardo,Giumanini,Strazzolini
, p. 609 - 627 (1994)
Some secondary and primary aromatic amines were variously N-alkylated and N-peralkylated by the aldehyde-sodium borohydride procedure in acidic aqueous solution. The procedure lends itself to the α-mono and α,α1-dideuterium labelling of the new N-substituent(s).
Buchwald-Hartwig Amination of (Hetero)Aryl Tosylates Using a Well-Defined N-Heterocyclic Carbene/Palladium(II) Precatalyst
Zhang, Yin,Lavigne, Guy,César, Vincent
, p. 7666 - 7673 (2015/08/18)
The cross-coupling of aryl tosylates with amines and anilines was achieved by using for the first time a Pd-NHC system based on the popular Pd-PEPPSI precatalyst platform in which the anchoring imidazol-2-ylidene ligand IPr (NMe2)2 incorporates two dimethylamino groups as backbone substituents enhancing both the electronic and steric properties of the carbene. The system optimization and its application scope are disclosed.
