1352733-07-3

Upstream product

• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 22252-14-8 (E)-3-(4-methylphenyl)-1-phenyl-2-propen-1-one 
• 14802-30-3 (E)-1-(4-methylphenyl)-3-phenyl-2-propen-1-one 
• 104-87-0 4-methyl-benzaldehyde 
• 122-00-9 para-methylacetophenone 
• 166824-01-7 α-phenyl p-methylcinnamyl alcohol 
• 1669-54-1 (E)-1-(4-methylphenyl)-3-phenyl-2-propen-1-ol 
• 62056-38-6 (E)-1-phenyl-3-p-tolylpropene 

Relevant academic research and scientific papers

Copper-catalyzed oxidative transformation of secondary alcohols to 1,5-disubstituted tetrazoles

A mild and convenient oxidative transformation of secondary alcohols to 1,5-disubstituted tetrazoles is uncovered by employing trimethylsilyl azide (TMSN3) as a nitrogen source in the presence of a catalytic amount of copper(II) perchlorate hexahydrate [Cu(ClO4)2 .6 H2O] (5 mol%) and 2,3-dichloro-5,6-dicyano-para- benzoquinone (DDQ) (1.2 equiv.) as an oxidant. This reaction is performed under ambient conditions and proceeds through C-C bond cleavage.

Implanting nitrogen into hydrocarbon molecules through Ci-H and Ci-C bond cleavages: A direct approach to tetrazoles

From simple beginnings: A novel Cu-promoted direct incorporation of nitrogen into simple hydrocarbon molecules under mild and neutral reaction conditions is described. 1,5-Disubstituted tetrazoles are efficiently constructed by two C sp 3i-H and one Ci-C bond cleavages (see scheme; TMS=trimethylsilyl). This protocol provides a new and unique strategy to functionalize simple and readily available hydrocarbon molecules.