1352807-22-7Relevant academic research and scientific papers
Chemoselective Organoclick-Click Sequence
Belkheira, Mokhtaria,El Abed, Douniazad,Pons, Jean-Marc,Bressy, Cyril
, p. 4254 - 4262 (2018/11/23)
A highly chemoselective bis-triazole synthesis based on a sequence organocatalyzed click reaction/copper-catalyzed click reaction is described in this paper. A range of bis-azides react with various ketones using proline catalysis through the aryl azide moiety while the alkyl azide one remains available for a metal-catalyzed triazole synthesis.
Organocatalytic synthesis of 1,2,3-triazoles from unactivated ketones and arylazides
Belkheira, Mokhtaria,El Abed, Douniazad,Pons, Jean-Marc,Bressy, Cyril
, p. 12917 - 12921 (2011/12/04)
Organo-click reaction: A new and complementary method to Huisgen's metal-catalyzed triazole synthesis is described using unactivated ketones and arylazides as the substrates and proline as an organocatalyst. Dramatic acceleration was observed for this reaction using microwave activation and high regio- and chemoselectivities were obtained for a wide range of ketones and arylazides (see scheme). Copyright
