1352834-05-9

Basic information

• Product Name: 4-[3-(4-fluorophenyl)-2-(4-fluorophenylimino)-4-oxothiazolidin-5-ylidenemethyl]benzoic acid
• CAS NO: 1352834-05-9
• Molecular Weight: 436.439
• Mol File: 1352834-05-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[3-(4-fluorophenyl)-2-(4-fluorophenylimino)-4-oxothiazolidin-5-ylidenemethyl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[3-(4-fluorophenyl)-2-(4-fluorophenylimino)-4-oxothiazolidin-5-ylidenemethyl]benzoic acid(1352834-05-9)
• EPA Substance Registry System: 4-[3-(4-fluorophenyl)-2-(4-fluorophenylimino)-4-oxothiazolidin-5-ylidenemethyl]benzoic acid(1352834-05-9)

Safety Data

• Hazardous Substances Data: 1352834-05-9(Hazardous Substances Data)

Upstream product

• 51964-15-9 3-(4-fluorophenyl)-2-(4-fluorophenylimino)-1,3-thiazolidine-4-one 
• 619-66-9 4-Carboxybenzaldehyde 
• 404-52-4 N,N’-di-(4-fluorophenyl)thiourea 
• 371-40-4 4-fluoroaniline 

Relevant articles and documents

Synthesis of novel 4-thiazolidione derivatives as antibacterial agents against drug-resistant Staphylococcus epidermidis

A series of novel substituted 4-thiazolidione derivatives were designed, synthesized, and evaluated in vitro for their antibacterial activities, in comparison with methicillin and ampicillin. Compounds (7d, 7h-k) exhibit good potency in inhibiting the growth of Staphylococcus epidermidis (MIC: 1.57-3.13 μM). Further antibacterial effects of compounds (7d, 7h-k) were investigated using clinical isolates (methicillin-resistant Staphylococcus epidermidis and methicillin-resistant Staphylococcus aureus), in comparison with methicillin and levofloxacin. Compound 7k showed the most potent antibacterial activities among the synthesized compounds.