135290-20-9

Basic information

• Product Name: Acetonitrile, (3-fluorophenoxy)- (9CI)
• Synonyms: Acetonitrile, (3-fluorophenoxy)- (9CI);2-(3-Fluorophenoxy)-acetonitrile
• CAS NO: 135290-20-9
• Molecular Formula: C₈H₆FNO
• Molecular Weight: 151.1377432
• Product Categories: HALIDE
• Mol File: 135290-20-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 229.4±15.0 °C(Predicted)
• Appearance: /
• Density: 1.185±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Acetonitrile, (3-fluorophenoxy)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Acetonitrile, (3-fluorophenoxy)- (9CI)(135290-20-9)
• EPA Substance Registry System: Acetonitrile, (3-fluorophenoxy)- (9CI)(135290-20-9)

Safety Data

• Hazardous Substances Data: 135290-20-9(Hazardous Substances Data)

Usage

General Description

Acetonitrile, (3-fluorophenoxy)- (9CI) is a chemical compound with the molecular formula C8H6FN and a molecular weight of 135.14 g/mol. It is a colorless liquid with a faint aromatic odor that is commonly used as a solvent in various chemical reactions and processes. This chemical is primarily used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. It is also utilized as a solvent for the extraction of fatty acids, in the manufacture of dyes, and as a stabilizer for the production of rubber. However, it is important to note that acetonitrile, (3-fluorophenoxy)- (9CI) is flammable and can be harmful if inhaled, ingested, or absorbed through the skin, and appropriate safety precautions should be taken when handling this chemical.

Upstream product

• 768-35-4 3-fluorophenylboronic acid 
• 590-17-0 cyanomethyl bromide 
• 372-20-3 3-fluorophenol 
• 107-14-2 chloroacetonitrile 

Downstream Products

• 1532534-65-8 C₂₀H₂₃FO₄ 
• 1532533-86-0 2-(3-fluorophenoxy)-1-(2,4,6-trihydroxyphenyl)ethanone 
• 1532534-39-6 1-(2,4-dihydroxy-5-propylphenyl)-2-(3-fluorophenoxy)ethanone 
• 1532534-13-6 1-(2,4-dihydroxy-5-methylphenyl)-2-(3-fluorophenoxy)ethanone 
• 1312414-45-1 2-(3-fluorophenoxymethyl)-5-(4-fluorophenyl)-6,7-dihydro-5H-thiazolo[5,4-c]pyridin-4-one 
• 1016796-64-7 2-(3-fluorophenoxy)thioacetamide 

Relevant articles and documents

Synthesis of aryloxyacetonitriles based on arylboronic acids with 2-bromoacetonitrile

A new and efficient protocol for the synthesis of aryloxyacetonitriles based on arylboronic acids with 2-bromoacetonitrile has been developed using eco-friendly hydrogen peroxide as oxidant under metal-free conditions. This method is compatible with arylboronic acid attached sensitive substituent and obtains desired product in moderate to good yield.

Heterocyclic compounds as P2X7 ion channel blockers

The present invention relates to a novel series of 4,5-diphenyl-2-amino-4,5-dihydro-imidazole derivatives of the formula II: 1 wherein R, R1, R2, R3, R4, R5, X and Y are as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are P2X7 ion channel blockers and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases having an inflammatory component, including inflammatory bowel disease, rheumatoid arthritis and disease conditions associated with the central nervous system, such as stroke, Alzheimer''s disease, etc.