1353013-63-4Relevant academic research and scientific papers
Reductive Hydrazination with Trichlorosilane: A Method for the Preparation of 1,1-Disubstituted Hydrazines
Wang, Tao,Di, Xiao,Wang, Chao,Zhou, Li,Sun, Jian
supporting information, p. 1900 - 1903 (2016/05/19)
A straightforward and facile method has been developed to prepare 1,1-disubstituted hydrazines via Lewis base promoted direct reductive hydrazination. Under the catalysis of hexamethylphosphoramide (HMPA) and N,N-dimethylacetamide (DMAc), respectively, various ketones and aldehydes could react with phenylhdrazines to prepare 1,1-disubstituted hydrazines with good to high yields.
A one-pot three-component reaction for the preparation of highly functionalized tryptamines
Yeo, Se Jeong,Liu, Yongxiang,Wang, Xiang
experimental part, p. 813 - 818 (2012/02/01)
We have developed a general one-pot method to provide highly functionalized tryptamine derivatives, via a Fischer indole type pathway. In this article, we demonstrate optimal conditions for a one-pot indole synthesis, allowing for the synthesis of a broad scope of 2-methyl tryptamine derivatives and a precursor for the synthesis of the core structure of some akuammiline alkaloids. Additionally, further modification of the indole products is described.
