1353013-91-8Relevant academic research and scientific papers
Synthesis and in vitro enzymatic and antiviral evaluation of phosphoramidate d4T derivatives as chain terminators
Yang, Shiqiong,Pannecouque, Christophe,Lescrinier, Eveline,Giraut, Anne,Herdewijn, Piet
, p. 146 - 153 (2012)
The anti-HIV activity of nucleoside analogues is highly related to their substrate specificity for cellular and viral kinase and, as triphosphate, for HIV-RT. A series of phosphoramidate d4T derivatives have been synthesized and evaluated as substrates fo
