13533-22-7

Basic information

• Product Name: Benzenamine, 4-chloro-N-(2-furanylmethylene)-
• CAS NO: 13533-22-7
• Molecular Formula: C11H8ClNO
• Molecular Weight: 205.644
• Mol File: 13533-22-7.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-chloro-N-(2-furanylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-chloro-N-(2-furanylmethylene)-(13533-22-7)
• EPA Substance Registry System: Benzenamine, 4-chloro-N-(2-furanylmethylene)-(13533-22-7)

Safety Data

• Hazardous Substances Data: 13533-22-7(Hazardous Substances Data)

Upstream product

• 98-01-1 furfural 
• 100-00-5 4-chlorobenzonitrile 
• 73221-41-7 (2E)-3-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]acrylaldehyde 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 202875-33-0 4-chloro-N-(1-(furan-2-yl)but-3-enyl)benzenamine 
• 1165779-61-2 4-chloro-N-(1-(furan-2-yl)-2-phenylethyl)benzenamine 
• 3237-22-7 2-cyano-3-(2-furanyl)acrylonitrile 
• 106-47-8 4-chloro-aniline 
• 1164485-17-9 (3aSR,4SR,9bSR)-8-chloro-4-(2'-furyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline 
• 95124-30-4 Picric acid; compound with (4-chloro-phenyl)-furan-2-ylmethyl-amine 
• 95124-31-5 1-(4-Chloro-phenyl)-1-furan-2-ylmethyl-3-phenyl-thiourea 
• 381177-35-1 1-allyl-2-(4-chloro-phenyl)-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid 
• 865353-67-9 (4-chloro-phenyl)-(1-furan-2-yl-3-methyl-but-3-enyl)-amine 
• 33829-87-7 4-chloro-N-(furan-2-yl-methyl)aniline 
• 64078-18-8 furan-2-carbothioic acid-(4-chloro-anilide) 

Relevant articles and documents

Rational Design of Cobalt-Platinum Alloy Decorated Cobalt Nanoparticles for One-Pot Synthesis of Imines from Nitroarenes and Aldehydes

Developing high-performance heterogeneous catalysts for one-pot reductive amination reactions is critically important for pharmaceutical and agrochemical synthetic industries. In this work, N-doped carbon nanotubes supported CoPt alloy decorated Co nanoparticles (NPs) are successfully fabricated. As a consequence, the resultant catalyst exhibits desirable activity, selectivity and stability toward the one-pot synthesis of imines. More importantly, the extensive experimental studies and density function theory (DFT) calculations results reveal that the high catalytic activity of the catalyst is mainly due to the co-existence of CoPt alloy NPs and Co NPs with Co?Nx active sites. The high selectivity of imines could be ascribed to the following aspects: (1) competitively preferred adsorption of nitroarenes to avoid side-hydrogenation of aldehydes; (2) weakened adsorption of imines to minimize its over-hydrogenation. This work may provide a promising direction and strategy to design high-performance reductive amination catalysts for industrial applications.

Heterogeneous Catalysis with Basic Compounds to Achieve the Synthesis and C-N Cleavage of Azetidin-2-ones under Microwave Irradiation

The synthesis of azetidin-2-ones with a completely heterogeneous catalysis is reported. The use of basic compounds as solid catalysts allowed for the synthesis of azetidin-2-ones under microwave irradiation without organic additives such as triethylamine. An excellent catalyst for this transformation was Mg-Al hydroxide (MAH). The present methodology offers the advantages of non-hazardous reaction conditions, short reaction times, high yields, and catalyst reusability. Different substitution groups were tested on the imines and acyl chlorides to explore the scope of the reaction. Unconventional N-C4 bond cleavage was detected in azetidin-2-ones. MAH was characterized by N 2 adsorption-desorption, X-ray diffraction (XRD), scanning electron microscopy (SEM), and high-resolution transmission electron microscopy (HR-TEM).

Solvent-free addition reaction of allylzinc bromide and aldimines

(Chemical Equation Presented) Barbier-type allylation of aldimines with allylzinc bromide took place rapidly under solvent-free conditions. The procedure is environmentally benign and operationally simple, has good regioselectivity, and gives good to exce