1353389-29-3Relevant academic research and scientific papers
Synthetic studies of stereocalpin A and its C5-epimer: Total synthesis of 11-epi- and 5,11-diepi-stereocalpin A
Reddy, K. Mahender,Shashidhar,Pottireddygari, Gurava Reddy,Ghosh, Subhash
, p. 5987 - 5991 (2011/11/29)
This Letter describes the synthetic studies of stereocalpin A and its C5-epimer. After various cyclization attempts, successful macrolactamization at 9-10 position was tried inorder to obtain stereocalpin A and its C5-epimer, which were accompanied by complete racemization and resulted in the synthesis of 11-epi- and 5,11-diepi-stereocalpin A. Highly functionalized octanoic acid motif of the depsipeptide was constructed by applying Paterson's aldol methodology, owing to its diversity in synthesizing various analogs of aliphatic acid.
