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1353548-02-3

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1353548-02-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1353548-02-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,3,5,4 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1353548-02:
(9*1)+(8*3)+(7*5)+(6*3)+(5*5)+(4*4)+(3*8)+(2*0)+(1*2)=153
153 % 10 = 3
So 1353548-02-3 is a valid CAS Registry Number.

1353548-02-3Relevant articles and documents

Target-triggered NIR emission with a large stokes shift for the detection and imaging of cysteine in living cells

Zhao, Chunchang,Li, Xiuai,Wang, Feiyi

, p. 1777 - 1781 (2014)

Background autofluorescence from biological systems generally reduces the sensitivity of a fluorescent probe for imaging biological targets. Addressing this challenge requires the development of fluorescent probes that produce emission in the near-infrared region. Herein, we report the design and synthesis of a fluorescent probe that generates an NIR emission with a large Stokes shift upon the selective response to Cys over Hcy and GSH. The probe is designed to consist of two Cys-sensing sites, an acrylate ester and an aldehyde installed ortho to each other. The reaction of the probe with Cys triggers an excited state intramolecular proton transfer process upon photo-excitation, thereby producing an NIR emission with a large Stokes shift. Accordingly, this probe hold great promise for the selective detection of Cys in biological systems. We further demonstrate the capacity of this probe for Cys imaging in living cells. How exciting! The reaction of the fluorescent probe PCys-B with cysteine (Cys) triggers an excited state intramolecular proton transfer process upon photoexcitation, thus producing an NIR emission with a large Stokes shift. This makes the probe promising for the selective detection of Cys in biological systems.

SPIROBODIPYs with spiropyran structure compound, preparation method and its use

-

, (2016/11/02)

The invention discloses a SPIROBODIPYs compound with the spiropyrane structure. The compound has the following structural general formula (refer to the Specification), wherein R1, R2, R3 and R4 are alkyl substituents or aromatic substituents, R5 is an alkyl substituent, an alcohol hydroxyl substituent or a substituent with triple bonds at the tail end. The invention further discloses the application of the SPIROBODIPYs compound to a fluorescence molecular probe. The SPIROBODIPYs compound can be applied to controllable detection of physiological and pathological process of cells, and can be used for building living cell acid organelles or used as a novel fluorescent dye of a fluorescence molecular probe for detecting the acid environment of cancer cells.

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