1353566-43-4

Basic information

• Product Name: (2R,3R)-2-methyl-2-(2-methyl-12-phenyl-2-((triethylsilyl)peroxy)dodecyl)-5-oxotetrahydrofuran-3-yl acetate
• Synonyms: (2R,3R)-2-methyl-2-(2-methyl-12-phenyl-2-((triethylsilyl)peroxy)dodecyl)-5-oxotetrahydrofuran-3-yl acetate
• CAS NO: 1353566-43-4
• Molecular Weight: 562.863
• Mol File: 1353566-43-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-2-methyl-2-(2-methyl-12-phenyl-2-((triethylsilyl)peroxy)dodecyl)-5-oxotetrahydrofuran-3-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-2-methyl-2-(2-methyl-12-phenyl-2-((triethylsilyl)peroxy)dodecyl)-5-oxotetrahydrofuran-3-yl acetate(1353566-43-4)
• EPA Substance Registry System: (2R,3R)-2-methyl-2-(2-methyl-12-phenyl-2-((triethylsilyl)peroxy)dodecyl)-5-oxotetrahydrofuran-3-yl acetate(1353566-43-4)

Safety Data

• Hazardous Substances Data: 1353566-43-4(Hazardous Substances Data)

Upstream product

• 103602-67-1 9-phenyl-1-bromononane 
• 637-59-2 1-Bromo-3-phenylpropane 
• 1353566-45-6 (11-bromododec-11-en-1-yl)benzene 
• 1353566-49-0 C₃₅H₆₄O₄Si₂ 
• 1353566-44-5 (R)-2-methyl-4-methylene-14-phenyl-2-((triethylsilyl)oxy)tetradecanal 
• 1353566-48-9 (R)-2-methyl-4-methylene-14-phenyl-2-((triethylsilyl)oxy)tetradecan-1-ol 
• 1353566-53-6 (R)-3,3,8,8-tetraethyl-5-methyl-5-(2-methylene-12-phenyldodecyl)-4,7-dioxa-3,8-disiladecane 
• 1353566-47-8 (R)-2-methyl-4-methylene-14-phenyl-1-((triethylsilyl)oxy)tetradecan-2-ol 
• 629-03-8 1 ,6-dibromohexane 
• 617-86-7 triethylsilane 
• 1353566-50-3 (2R,3R)-2-methyl-2-(2-methylene-12-phenyldodecyl)-5-oxotetrahydrofuran-3-yl acetate 

Downstream Products

• 162559-02-6 (+)-plakortolide E 
• 1353566-51-4 (1S,4R,5R)-4-(2-hydroxy-2-methyl-12-phenyldodecyl)-4-methyl-3,6-dioxabicyclo[3.1.0]hexan-2-one 
• 1353566-52-5 C₃₀H₅₀O₄Si 
• 1353566-42-3 (4R,5R)-4-hydroxy-5-((R)-2-hydroxy-2-methyl-12-phenyldodecyl)-5-methyldihydrofuran-2(3H)-one 

Relevant articles and documents

Total synthesis of seco-plakortolide e and (-)-ent-plakortolide I: Absolute configurational revision of natural plakortolide i

A first total synthesis of (-)-ent-plakortolide I and seco-plakortolide E was accomplished from (S)-2-methylglycidol. The relevant key reactions involve a diastereoselective Mukaiyama aldol reaction, a regioselective hydroperoxysilylation, and elaboration of the 1,2-dioxane ring by intramolecular Michael addition of a hydroperoxide group to a butenolide. This synthesis allowed the revision of the absolute configuration of plakortolide I and structural revision of plakortolide E.