1353566-63-8

Basic information

• Product Name: (2S)-2-(benzyloxy)-5-hexenoic acid
• Synonyms: (2S)-2-(benzyloxy)-5-hexenoic acid
• CAS NO: 1353566-63-8
• Molecular Weight: 220.268
• Mol File: 1353566-63-8.mol

Chemical Properties

• CAS DataBase Reference: (2S)-2-(benzyloxy)-5-hexenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-(benzyloxy)-5-hexenoic acid(1353566-63-8)
• EPA Substance Registry System: (2S)-2-(benzyloxy)-5-hexenoic acid(1353566-63-8)

Safety Data

• Hazardous Substances Data: 1353566-63-8(Hazardous Substances Data)

Upstream product

• 1353566-61-6 (5S)-5-(benzyloxy)-6-[(4-methoxybenzyl)oxy]-1-hexene 
• 100-39-0 benzyl bromide 
• 876144-69-3 (S)-1-(4-Methoxy-benzyloxy)-hex-5-en-2-ol 
• 83861-87-4 (2S)-2-(benzyloxy)-5-hexen-1-ol 

Downstream Products

• 1353566-65-0 (1R)-1-[(4R,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]butyl (2S)-2-(benzyloxy)-5-hexenoate 

Relevant articles and documents

Titanium(IV)-promoted regioselective nucleophilic ring-opening reaction of chiral epoxyallyl alcohols with acids as a tool for ready access to chiral 1,2,3-triol monoesters: Application to stereoselective total synthesis of macrolides

Titanium(IV)-promoted regioselective ring-opening reaction of chiral epoxy-allyl alcohols (Sharpless conditions as the key strategic step) is developed as a tool for ready access to chiral 5,6-dihydroxyoct-7-en-4-yl alkoxylates. Later, the synthetic utility of products thereof was demonstrated through the RCM based stereoselective synthesis of various natural products.