135357-73-2

Upstream product

• 67-56-1 methanol 
• 17812-27-0 cis-5-norbornene-endo-2,3-dicarboxylic anhydride 
• 129-64-6 3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride 
• 2746-19-2 (1R,2R,6S,7S)-4-oxa-tricyclo[5.2.1.0^2,6]dec-8-ene-3,5-dione 
• 4098-47-9 Dimethyl norbornane-trans-2,3-dicarboxylate 
• 123286-70-4 (1S,2S,3S,4R)-endo-3-(methoxycarbonyl)-bicyclo[2.2.1]hept-5-en-exo-2-carboxylic acid 
• 3014-58-2 dimethyl (exo,endo)-bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate 
• 624-49-7 dimethylfumarate 
• 14166-28-0 exo-bicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride 
• 29745-04-8 norcantharidin 
• 135029-24-2 (1S,2R,3S,4S)-2-<(S)-Mandeloxycarbonyl>-7-oxabicyclo<2.2.1>heptane-3-carboxylic Acid 
• 130362-20-8 (1S,2R,3S,4R)-7-Oxa-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid 2-((S)-methoxycarbonyl-phenyl-methyl) ester 3-methyl ester 
• 542-92-7 cyclopenta-1,3-diene 
• 130362-19-5 (1R,2S,3R,4S)-2-<(R)-Mandeloxycarbonyl>-7-oxabicyclo<2.2.1>heptane-3-carboxylic Acid 

Relevant academic research and scientific papers

Cinchona alkaloid derivative modified Fe3O4nanoparticles for enantioselective ring opening of: Meso -cyclic anhydrides

In the present work, the molecular framework of quinidine was modified at the methoxy functional group of the C6′ carbon of the quinoline moiety with a long-chain carboxylic acid group (-COOH) and it was used as a capping agent during the synthesis of Fe3

Catalytic asymmetric desymmetrization of prochiral and meso compounds

The present invention relates to methods for the synthesis of chiral non-racemic products, e.g., enantiomerically-enriched hemiesters, from prochiral and meso starting materials, e.g., prochiral and meso cyclic anhydrides. The present invention also relates to catalysts for the aforementioned methods, and methods for synthesizing these catalysts.

Enzymatic optical resolution of norbornanecarboxylic esters using Pig Liver Esterase

The hydrolysis of a series of norbornane-type carboxylic esters catalyzed by pig liver esterase (PLE) has been investigated.It was found that an exo-ester function (syn to the C7 methylene group) is hydrolyzed with high preference.Enantioselective hydrolysis can be accomplished when a vicinal carbonyl-containing function (ester, formyl, acetyl) is present in a trans position with respect to the exo ester.The regiospecifity of the enzymatic hydrolysis has been used for the separation of exo/endo mixtures of the cycloadducts derived from cyclopentadiene and alkene esters.The regiospecifity and enantioselectivity of the enzymatic hydrolysis of norbornane-type esters were analyzed in terms of Tamm's substrate model and also by Griengl's method.

Highly Effective and Practical Enantioselective Synthesis of Half-Esters of Bicycloheptanedicarboxylic Acid

An effective and practical enantioselective synthesis of half-esters of bicycloheptane-2,3-dicarboxylic acid was developed by enantioselective fission of ?-symmetrical cyclic anhydrides with chiral mandelic acid derivatives, followed by deprotectio

Optical and Neutron Inelastic Scattering Study of 2,3-Dimethylnorbornanes

We have measured the infrared, Raman, and neutron vibrational spectra of the 2,3-dimethylnorbornanes with two CH3 or CD3 groups in the 2- and 3-exo or endo positions.A normal-coordinate analysis has been carried out.No coupling reflecting the strain due to the methyl group appears in the C-CH3 bending and torsional modes of the trans isomer, but appears in the cis-exo isomer (average value 23 cm-1) and in the cis-endo isomer (average value 28 cm-1.The frequencies are used for the determination of the thermodynamic contribution to the standard free energy differences.