17812-27-0

Upstream product

• 826-62-0 5-norbornene-2,3-dicarboxylic anhydride 
• 129-64-6 bicyclo<2.2.1>-5-hepten-2endo,3endo-dicarboxylic anhydride 
• 129-64-6 3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride 
• 2746-19-2 (1R,2R,6S,7S)-4-oxa-tricyclo[5.2.1.0^2,6]dec-8-ene-3,5-dione 

Downstream Products

• 167390-18-3 C₄₀H₄₇NO₆S 
• 336185-22-9 3-{[(benzyloxy)carbonyl]amino}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid 
• 1071519-98-6 methyl 3-{[(benzyloxy)carbonyl]amino}bicyclo[2.2.1]hept-5-ene-2-carboxylate 
• 1355590-28-1 4-endo-dihydronorbornyl benzoic acid 
• 14805-28-8 2-benzenesulfonyloxy-(3ac,7ac)-hexahydro-4r,7c-methano-isoindole-1,3-dione 
• 76198-36-2 di-endo-3-aminobicyclo[2.2.1]heptane-2-carboxylic acid 
• 130464-53-8 (1S,2S,3R,4R)-Bicyclo[2.2.1]heptane-2,3-dicarboxylic acid 2-((S)-methoxycarbonyl-phenyl-methyl) ester 3-methyl ester 

Relevant academic research and scientific papers

ENDO-METHYLENE HEXAHYDROPHTHALIC ANHYDRIDE AND PRODUCTION METHOD THEREOF

The present invention belongs to the field of organic chemical synthesis, and discloses hexahydro-3,6-methanophthalic anhydride and a method of producing the same. The method uses maleic anhydride and mixed C5s as raw materials, generates Nadic anhydride by absorbing cyclopentadiene with maleic anhydride directly at a temperature of 0-5°C, and crystallizes to obtain a pure product; and a Cu-Ni/ZnO-ZrO2 or Co-Ni/ZnO-ZrO2 catalyst is added to the generated Nadic anhydride, carrying out a catalytic hydrogenation reaction in a high-pressure autoclave for 4-6 hours at a temperature of 100-140°C and under a hydrogen pressure of 1-4 MPa, the catalyst is filtered after cooling, and reduced pressure distilling to obtain the hexahydro-3,6-methanophthalic anhydride. Compared with the prior art, the present invention prepares the Nadic anhydride by using mixed C5s, an inexpensive by-product of ethylene, as a raw material, and further synthesizes hexahydro-3,6-methanophthalic anhydride while obtaining a chemical raw material de-cyclized C5s at the same time, enhances the in-depth processing of mixed C5s, and can be used widely in industrial production.

METHOD OF SEPARATING STEREOISOMERS OF NORBORNENE, DICARBOXYLIC ACID HAVING NORBORNANE STRUCTURE, OR DERIVATIVE THEREOF

A method of efficiently extracting a high-purity stereoisomer from a mixture comprising the endo isomer and the exo isomer of a dicarboxylic acid having a norbomene or norbomane structure, or a derivative thereof. The present invention relates to a method of separating the endo isomer and the exo isomer of a dicarboxylic acid represented by a general formula (1) or (2) or a derivative thereof, and includes the step of stirring and mixing a mixture comprising mainly the endo isomer of the dicarboxylic acid represented by the general formula (1) or (2) or a derivative thereof, and the exo isomer of the dicarboxylic acid represented by the general formula (1) or (2) or a derivative thereof, with a basic compound and a solvent. (wherein, R1 to R8 represent a hydrogen atom, methyl group, ethyl group, or butyl group), (wherein, R'1 to R'10 represent a hydrogen atom, methyl group, ethyl group, or butyl group)