1353879-69-2Relevant articles and documents
Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors
Raje, Mithun R.,Knott, Kenneth,Kharel, Yugesh,Bissel, Philippe,Lynch, Kevin R.,Santos, Webster L.
, p. 183 - 194 (2012/02/06)
Sphingosine kinase (SphK) has emerged as an attractive target for cancer therapeutics due to its role in cell survival. SphK phosphorylates sphingosine to form sphingosine 1-phosphate (S1P), which has been implicated in cancer growth and survival. SphK ex