1353896-75-9Relevant academic research and scientific papers
A multi-component domino reaction for the direct access to polyfunctionalized indoles via intermolecular allylic esterification and indolation
Jiang, Bo,Yi, Mian-Shuai,Shi, Feng,Tu, Shu-Jiang,Pindi, Suresh,McDowell, Patrick,Li, Guigen
, p. 808 - 810 (2012)
A novel multi-component reaction for the synthesis of polyfunctionalized indoles and bis-indoles has been established. The reaction pathways were controlled by varying enamines with different substitution patterns to give polyfunctionalized indoles and bis-indoles selectively. The reaction proceeds at a fast speed within 15-30 min with water as the major byproduct, which makes work-up convenient.
