13539-26-9Relevant articles and documents
Formation of polyhydroxylated isoflavones from the isoflavones genistein and biochanin a by bacteria isolated from tempe
Klus, Klaus,Barz, Wolfgang
, p. 1045 - 1048 (1998)
Two tempe-derived bacterial strains identified as Micrococcus or Arthrobacter species were shown to transform the 5-hydroxyisoflavones biochanin A and genistein to polyhydroxylated isoflavones by hydroxylation reactions at positions C-6 and C-8. Both strains transformed genistein to 5,6,7,4'-tetrahydroxyisoflavone and 5,7,8,4'-tetrahydroxyisoflavone and biochanin A to 4'-methoxy-5,7,8,-trihydroxyisoflavone, whereas only strain I converted biochanin A to 4'-methoxy-5,6,7-trihydroxyisoflavone. The structures of these transformation products were elucidated by spectroscopic techniques.
α-Glucosidase inhibition of 6-hydroxyflavones. Part 3: Synthesis and evaluation of 2,3,4-trihydroxybenzoyl-containing flavonoid analogs and 6-aminoflavones as α-glucosidase inhibitors
Gao, Hong,Kawabata, Jun
, p. 1661 - 1671 (2007/10/03)
The SAR studies suggested that the C-ring of baicalein (1) was not necessary for the activity, and validated the importance of 2,3,4- trihydroxybenzoyl structure of 1. Thus, a series of 2,3,4-trihydroxybenzoyl- containing flavonoid analogs were investigat
Isoflavones from Podocarpus amarus
Carman, Raymond M.,Russel-Maynard, John K. L.,Schumann, Russell C.
, p. 485 - 496 (2007/10/02)
The isoflavone irisolidone is a major constituent of Podocarpus amarus hearthwood.Its structure has been securely established by 13C n.m.r. studies upon a range of derivatives.The isoflavones biochanin A, genistein and daidzein are also present in the tre