1353997-04-2 Usage
Description
(R)-1-Benzyl-3-bromopiperidine is a chemical compound belonging to the class of piperidine derivatives. It is a chiral molecule characterized by a benzyl group attached to the piperidine ring and a bromine atom at the 3-position. This unique structure endows it with potential utility in organic synthesis and medicinal chemistry.
Uses
Used in Pharmaceutical Drug Development:
(R)-1-Benzyl-3-bromopiperidine is used as a key intermediate for the development of pharmaceutical drugs. Its structural properties and reactivity make it a valuable building block for the synthesis of diverse chemical compounds, contributing to the creation of novel therapeutic agents.
Used in Organic Synthesis:
In the field of organic chemistry, (R)-1-Benzyl-3-bromopiperidine is used as a versatile building block for the synthesis of various chemical compounds. Its unique molecular structure allows for further functionalization and modification, facilitating the development of new molecules with specific properties and applications.
Used in Medicinal Chemistry:
(R)-1-Benzyl-3-bromopiperidine is also utilized in medicinal chemistry as a starting material for the design and synthesis of new drugs. Its chiral nature and functional groups make it an attractive candidate for the development of enantiomerically pure compounds with potential therapeutic benefits.
Used in Research and Development:
(R)-1-Benzyl-3-broMo-piperidine is used as a research tool in the field of drug discovery and development. It aids scientists in understanding the structure-activity relationships of various biologically active molecules and assists in the optimization of drug candidates for improved efficacy and safety.
It is important to handle (R)-1-Benzyl-3-bromopiperidine with caution due to its potential reactivity and toxicity. Proper safety measures and guidelines should be followed during its use in research and development settings.
Check Digit Verification of cas no
The CAS Registry Mumber 1353997-04-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,3,9,9 and 7 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1353997-04:
(9*1)+(8*3)+(7*5)+(6*3)+(5*9)+(4*9)+(3*7)+(2*0)+(1*4)=192
192 % 10 = 2
So 1353997-04-2 is a valid CAS Registry Number.
1353997-04-2Relevant articles and documents
Regioselective copper(II)-mediated bromoamination of unfunctionalized olefins: An efficient route to N-heterocyclic compounds
Liu, Gong-Qing,Ding, Zhen-Ying,Zhang, Li,Li, Ting-Ting,Li, Lin,Duan, Lili,Li, Yue-Ming
, p. 2303 - 2310 (2014/07/21)
Bromoamination of unfunctionalized olefins was realized under mild conditions using copper(II) bromide (CuBr2) as both reaction promoter and bromine source. The reactions could be carried out under open air at ambient temperature, and both N-alkylated and N-tosylated substrates could be converted to the corresponding N-heterocyclic compounds in high regioselectivity and good isolated yields. A variety of biologically important structures could be obtained via subsequent nucleophilic substitution reactions.
Synthesis and reaction of 1-azabicyclo[3.1.0]hexane
Hayashi, Kazuhiko,Kujime, Eiko,Katayama, Hajime,Sano, Shigeki,Shiro, Motoo,Nagao, Yoshimitsu
experimental part, p. 1142 - 1146 (2010/03/31)
The effective formation of 1-azabicyclo[3.1.0]hexane (5) by treatment of 2-(bromomethyl)pyrrolidine hydrobromide (4) with n-BuLi was established, with the reaction occurring by a rational reaction pathway via the open chain transition state 8 based on int
