135500-41-3

Upstream product

• 127708-18-3 (3R,5R,8aR)-5-(2-[1,3]Dioxolan-2-yl-ethyl)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 135384-10-0 1-[(R)-2-(2-[1,3]Dioxolan-2-yl-ethyl)-1-((R)-2-hydroxy-1-phenyl-ethyl)-piperidin-2-yl]-ethanol 
• 135384-12-2 1-[(R)-1-Benzyl-2-(2-[1,3]dioxolan-2-yl-ethyl)-piperidin-2-yl]-ethanone 
• 135384-11-1 1-[(R)-1-Benzyl-2-(2-[1,3]dioxolan-2-yl-ethyl)-piperidin-2-yl]-ethanol 
• 135500-40-2 (+)-1-benzyl-1-azaspiro<5.5>undecan-7-one 
• 135384-13-3 (R)-1-Benzyl-1-aza-spiro[5.5]undec-8-en-7-one 
• 88056-92-2 (-)-2-cyano-6-phenyloxazolopiperidine 
• 135384-14-4 (6R,7R)-1-Benzyl-7-butyl-1-aza-spiro[5.5]undecan-7-ol 

Downstream Products

• 135500-42-4 (6R,7S,8S)-1-Benzyl-7-butyl-1-aza-spiro[5.5]undecan-8-ol 
• 135500-43-5 (6R,7R,8R)-1-Benzyl-7-butyl-1-aza-spiro[5.5]undecan-8-ol 

Relevant academic research and scientific papers

Asymmetricsynthesis. XXXII. Formalsynthesisof (-) - Perhydrohistrionicotoxin

The synthesis of (-)-depentylperhydrohistrionicotoxin 2 from the 2-cyano-6-oxazolopiperidine synthon (-) 3 has been achieved. The spiro skeleton was formed by an aldol cyclization of a methyl ketone and an aldehyde function belonging to chains borne at C-