1355034-84-2Relevant articles and documents
Facile synthesis of 1,2,3-triazole analogs of SGLT2 inhibitors by 'click chemistry'
Li, Lan-Tao,Zhou, Li-Fei,Li, Yan-Jun,Huang, Juan,Liu, Rui-Hua,Wang, Bin,Wang, Peng
, p. 642 - 644 (2012/03/11)
Novel analogs of SGLT2 inhibitors containing the 1,2,3-triazole motif were designed and synthesized for urinary glucose excretion evaluation. The C-glucosides with triazole aglycone can be easily constructed by click chemistry. Most of the synthesized compounds increased urinary glucose excretion and demonstrated inhibition of glucose transport.