135582-86-4

Upstream product

• 134038-72-5 (S)-3-benzyloxycarbonylamino-2-hydroxy-1-(o-nitrobenzoyloxy)propane 
• 77-76-9 2,2-dimethoxy-propane 
• 134038-71-4 (S)-4-benzyloxycarbonylaminomethyl-2,2-dimethyl-1,3-dioxolane 
• 135582-93-3 (S)-3-[N-(benzyloxycarbonyl)amino]-1,2-propanediol 

Downstream Products

• 134038-74-7 benzyl (S)-5-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate 
• 135638-41-4 (R)-3-benzyloxycarbonyl-5-<(Z)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)vinyl>-2,2-dimethyl-1,3-oxazolidine 
• 134038-76-9 (R)-3-benzyloxycarbonyl-5-<(S)-N-tert-butoxycarbonylalanin-3-yl>-2,2-dimethyl-1,3-oxazolidine 
• 135582-94-4 (R)-3-benzyloxycarbonyl-5-<(S)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)ethyl>-2,2-dimethyl-1,3-oxazolidine 
• 134038-75-8 (R)-3-benzyloxycarbonyl-5-<(E)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)vinyl>-2,2-dimethyl-1,3-oxazolidine 
• 134038-86-1 benzyl 2(S)-(5-benzyloxycarbonylamino-2(S)-tert-butoxycarbonylamino-4(R)-hydroxypentanoylamino)-3-[4,4'-bisbenzyloxy-3'-(2(S)-benzyloxycarbonylamino-2-pentafluorophenyloxycarbonylethyl)biphenyl-3-yl]propionate 
• 134038-76-9 (R)-3-Benzyloxycarbonyl-5-<(S)-N-tert-butoxycarbonylalanin-3-yl>-2,2-dimethyl-1,3-oxazolidine 
• 135582-94-4 (R)-3-benzyloxycarbonyl-5-<(S)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)ethyl>-2,2-dimethyl-1,3-oxazolidine 
• 134038-87-2 benzyl 5,17-bisbenzyloxy-14(S)-benzyloxycarbonylamino-11(S)-(3-benzyloxycarbonylamino-2(R)-hydroxypropyl)-10,13-dioxo-9,12-diazatricyclo[14.3.1.12,6]-henicosa-1(19),2,4,6(21),16(20),17-hexaene-8(S)-carboxylate 
• 145240-76-2 2(S)-benzyloxycarbonylamino-3-{4,4'-bisbenzyloxy-3'-[2(S)-benzyloxycarbonyl-2-(5-benzyloxycarbonylamino-2(S)-tert-butoxycarbonylamino-4(R)-hydroxypentanoylamino)ethyl]biphenyl-3-yl}propionic acid 
• 134038-73-6 benzyl (S)-5-hydroxymethyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate 

Relevant academic research and scientific papers

The Synthesis of Biphenomycin B

Biphenomycin B, a highly potent antibiotic against Gram-negative, β-lactam-resistant bacteria, which was previously isolated from culture filtrates of Streptomyces griseorubiginosus No. 43708, has now been synthesized.

Total synthesis of the biphenomycins; II. Synthesis of protected (2S,4R)-4-hydroxyornithines

Improved synthetic methods for the preparation of three differently protected (2S,4R)-4-hydroxyornithine (10, 16, 24) have been developed which obviously can be used for the construction of the other stereoisomers. Formation of the corresponding α,β-dideh