135582-94-4

Basic information

• Product Name: (R)-3-benzyloxycarbonyl-5-<(S)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)ethyl>-2,2-dimethyl-1,3-oxazolidine
• Synonyms: (R)-3-benzyloxycarbonyl-5-<(S)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)ethyl>-2,2-dimethyl-1,3-oxazolidine
• CAS NO: 135582-94-4
• Molecular Weight: 436.505
• Mol File: 135582-94-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-3-benzyloxycarbonyl-5-<(S)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)ethyl>-2,2-dimethyl-1,3-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-benzyloxycarbonyl-5-<(S)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)ethyl>-2,2-dimethyl-1,3-oxazolidine(135582-94-4)
• EPA Substance Registry System: (R)-3-benzyloxycarbonyl-5-<(S)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)ethyl>-2,2-dimethyl-1,3-oxazolidine(135582-94-4)

Safety Data

• Hazardous Substances Data: 135582-94-4(Hazardous Substances Data)

Upstream product

• 135638-41-4 (R)-3-benzyloxycarbonyl-5-<(Z)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)vinyl>-2,2-dimethyl-1,3-oxazolidine 
• 911225-68-8 methyl (2S,4R)-5-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-4-hydroxypentanoate 
• 77-76-9 2,2-dimethoxy-propane 
• 911225-69-9 (2S,4R)-2-tert-butoxycarbonylamino-4-iodomethyl-4-butanolide 
• 911225-54-2 (2S,4R)-2-azido-4-[(tert-butyldiphenylsilyloxy)methyl]-4-butanolide 
• 911225-55-3 (2S,4R)-2-amino-4-[(tert-butyldiphenylsilyloxy)methyl]-4-butanolide 
• 911225-56-4 (2S,4R)-2-tert-butoxycarbonylamino-4-[(tert-butyldiphenylsilyloxy)methyl]-4-butanolide 
• 911225-58-6 methyl (2S,4R)-2-tert-butoxycarbonylamino-4-hydroxy-5-tert-butyldiphenylsilyloxy pentanoate 
• 501-53-1 benzyl chloroformate 
• 135582-88-6 (S)-3-benzyloxycarbonyl-5-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine 
• 135582-87-5 (S)-methyl 3-(benzyloxycarbonylamino)-2-hydroxypropanoate 
• 42491-79-2 (2S)-3-{[(benzyloxy)carbonyl]amino}-2-hydroxypropanoic acid 
• 135582-86-4 (S)-3-benzyloxycarbonyl-2,2-dimethyl-5-o-nitrobenzoyloxymethyl-1,3-oxazolidine 
• 134038-72-5 (S)-3-benzyloxycarbonylamino-2-hydroxy-1-(o-nitrobenzoyloxy)propane 

Downstream Products

• 134038-76-9 (R)-3-Benzyloxycarbonyl-5-<(S)-N-tert-butoxycarbonylalanin-3-yl>-2,2-dimethyl-1,3-oxazolidine 
• 134038-76-9 (R)-3-benzyloxycarbonyl-5-<(S)-N-tert-butoxycarbonylalanin-3-yl>-2,2-dimethyl-1,3-oxazolidine 
• 134038-86-1 benzyl 2(S)-(5-benzyloxycarbonylamino-2(S)-tert-butoxycarbonylamino-4(R)-hydroxypentanoylamino)-3-[4,4'-bisbenzyloxy-3'-(2(S)-benzyloxycarbonylamino-2-pentafluorophenyloxycarbonylethyl)biphenyl-3-yl]propionate 
• 100217-74-1 biphenomycin B 
• 134038-87-2 benzyl 5,17-bisbenzyloxy-14(S)-benzyloxycarbonylamino-11(S)-(3-benzyloxycarbonylamino-2(R)-hydroxypropyl)-10,13-dioxo-9,12-diazatricyclo[14.3.1.12,6]-henicosa-1(19),2,4,6(21),16(20),17-hexaene-8(S)-carboxylate 
• 145240-76-2 2(S)-benzyloxycarbonylamino-3-{4,4'-bisbenzyloxy-3'-[2(S)-benzyloxycarbonyl-2-(5-benzyloxycarbonylamino-2(S)-tert-butoxycarbonylamino-4(R)-hydroxypentanoylamino)ethyl]biphenyl-3-yl}propionic acid 

Relevant articles and documents

First synthesis of polyoxin M

Chiral enolate derived from (4R)-4-tert-butyldiphenylsilyloxymethyl-4-butanolide 10 with lithium hexamethyldisilyazide (LiHMDS) was treated with trisyl azide, followed by addition of TMSCl to give (2S,4R)-2-azido-4-[(tert-butyldiphenylsilyloxy)methyl]-4-b

Total synthesis of the biphenomycins; II. Synthesis of protected (2S,4R)-4-hydroxyornithines

Improved synthetic methods for the preparation of three differently protected (2S,4R)-4-hydroxyornithine (10, 16, 24) have been developed which obviously can be used for the construction of the other stereoisomers. Formation of the corresponding α,β-dideh