1355988-71-4Relevant articles and documents
Difluoroalkylation/C-H Annulation Cascade Reaction Induced by Visible-Light Photoredox Catalysis
Li, Jin,Chen, Jingzhi,Jiao, Wei,Wang, Guoqiang,Li, Ying,Cheng, Xu,Li, Guigen
, p. 9992 - 10001 (2016)
We report the first example of difluoroalkylation/C-H annulation cascade reactions of cyclopropyl olefins induced by visible-light photoredox catalysis regioselectively affording partially hydrogenated naphthalenes and quinolines with a variety of difluorinated side chains. The alkylation reagent could be extended to monofluoro and trifluoro reagents, nitrile and malonate. The regioselectivity was investigated by means of density functional theory calculations.