400614-05-3 Usage
Description
CYCLOPROPYL 2-METHOXYPHENYL KETONE, also known as 2-Cyclopropyl-2-methoxyacetophenone, is a chemical compound with the molecular formula C11H12O2. It is a ketone with a cyclopropyl group and a methoxyphenyl group attached to the carbonyl carbon. This versatile chemical is widely used in the synthesis of pharmaceuticals, agrochemicals, and organic compounds, as well as in the production of fragrance and flavor ingredients. Its potential applications extend to material science and as an intermediate in organic synthesis.
Uses
Used in Pharmaceutical Industry:
CYCLOPROPYL 2-METHOXYPHENYL KETONE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with improved efficacy and safety profiles.
Used in Agrochemical Industry:
CYCLOPROPYL 2-METHOXYPHENYL KETONE is used as a building block in the production of agrochemicals, helping to create effective and environmentally friendly solutions for pest control and crop protection.
Used in Fragrance and Flavor Industry:
CYCLOPROPYL 2-METHOXYPHENYL KETONE is used as a component in the creation of fragrances and flavorings, adding unique scents and tastes to a variety of consumer products.
Used in Material Science:
CYCLOPROPYL 2-METHOXYPHENYL KETONE is used in the field of material science for its potential to contribute to the development of innovative materials with enhanced properties.
Used in Organic Synthesis:
CYCLOPROPYL 2-METHOXYPHENYL KETONE is used as an intermediate in organic synthesis, enabling the production of a wide range of organic compounds for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 400614-05-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,0,6,1 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 400614-05:
(8*4)+(7*0)+(6*0)+(5*6)+(4*1)+(3*4)+(2*0)+(1*5)=83
83 % 10 = 3
So 400614-05-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O2/c1-13-10-5-3-2-4-9(10)11(12)8-6-7-8/h2-5,8H,6-7H2,1H3
400614-05-3Relevant articles and documents
Ni/Ti Dual Catalytic Cross-Coupling of Nitriles and Organobromides to Access Ketones
Chenniappan, Vinoth Kumar,Silwal, Sajan,Rahaim, Ronald J.
, p. 4539 - 4544 (2018/05/23)
Herein, we report the development of a dual catalytic approach for the cross-coupling of nitriles with aryl- and aliphatic-bromides. A titanium(III) catalyst is used to activate nitriles enabling their coupling with organobromides through a nickel catalyst. The Ni/Ti system efficiently prepared unsymmetrical ketones with good chemoselectivity and could selectively couple a bromide in the presence of other functionalizable handles.
Calcium receptor antagonist
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Page 29, (2010/11/30)
A compound of the formula [I] wherein R1 is optionally substituted aryl group or optionally substituted heteroaryl group; R2 is optionally substituted C1-6 alkyl group, C3-7 cycloalkyl group and the like; R3 is hydrogen atom, C1-6 alkyl group, hydroxyl group and the like; R4 is hydrogen atom, C1-6 alkyl group and the like; R5 and R6 are each C1-6 alkyl group and the like; R7 is optionally substituted aryl group or optionally substituted heteroaryl group; X1, X2 and X3 are each C1-6 alkylene group and the like; and X4 and X5 are each a single bond, methylene group and the like, a salt thereof, a solvate thereof or a prodrug thereof, and a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist and a therapeutic agent for osteoporosis, are provided. The compound of the present invention is useful as a therapeutic drug of diseases accompanied by abnormal calcium homeostasis, or osteoporosis, hypoparathyreosis, osteosarcoma, periodontal disease, bone fracture, steoarthrosis, chronic rheumatoid arthritis, Paget's disease, humoral hypercalcemia, autosomal dominant hypocalcemia and the like. In addition, an intermediate for the compound is provided.
