1356035-27-2

Basic information

• Product Name: N-(5-(2-(cyanoimino)-1-(4-(2-cyanopropan-2-yl)phenyl)-3-methyl-2,3-dihydro-1H-imidazo[4,5-c]quinolin-8-yl)-2-methoxypyridin-3-yl)benzenesulfonamide
• Synonyms: N-(5-(2-(cyanoimino)-1-(4-(2-cyanopropan-2-yl)phenyl)-3-methyl-2,3-dihydro-1H-imidazo[4,5-c]quinolin-8-yl)-2-methoxypyridin-3-yl)benzenesulfonamide
• CAS NO: 1356035-27-2
• Molecular Weight: 628.714
• Mol File: 1356035-27-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(5-(2-(cyanoimino)-1-(4-(2-cyanopropan-2-yl)phenyl)-3-methyl-2,3-dihydro-1H-imidazo[4,5-c]quinolin-8-yl)-2-methoxypyridin-3-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-(2-(cyanoimino)-1-(4-(2-cyanopropan-2-yl)phenyl)-3-methyl-2,3-dihydro-1H-imidazo[4,5-c]quinolin-8-yl)-2-methoxypyridin-3-yl)benzenesulfonamide(1356035-27-2)
• EPA Substance Registry System: N-(5-(2-(cyanoimino)-1-(4-(2-cyanopropan-2-yl)phenyl)-3-methyl-2,3-dihydro-1H-imidazo[4,5-c]quinolin-8-yl)-2-methoxypyridin-3-yl)benzenesulfonamide(1356035-27-2)

Safety Data

• Hazardous Substances Data: 1356035-27-2(Hazardous Substances Data)

Upstream product

• 1356035-54-5 N-(8-bromo-1-(4-(2-cyanopropan-2-yl)phenyl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-ylidene)cyanamide 
• 1086063-47-9 N-(5-bromo-2-methoxypyridin-3-yl)benzenesulphonamide 
• 1356035-53-4 (2-(cyanoimino)-1-(4-(2-cyanopropan-2-yl)phenyl)-3-methyl-2,3-dihydro-1H-imidazo[4,5-c]quinolin-8-yl)boronic acid 
• 884495-39-0 5-bromo-2-(methyloxy)-3-pyridinamine 
• 98-09-9 benzenesulfonyl chloride 

Relevant articles and documents

SUBSTITUTED IMIDAZOQUINOLINE DERIVATIVES AS KINASE INHIBITORS

The present invention relates to substituted imidazo[4,5-c]quinoline derivatives, the compounds of formula (I), wherein R1 R2, R3, R4, R5, R6 and R7 are as defined in the specification, processes for their preparation, pharmaceutical compositions comprising compounds of formula (I), and their use in the treatment of diseases or disorders mediated by one or more kinases, particularly proliferative diseases or disorders such as cancer. These compounds can also be used in the treatment of inflammatory diseases and angiogenesis related disorders.