13563-36-5

Upstream product

• 1266244-67-0 (2-methyl-3-oxo-2,3-dihydro-pyridazin-4-ylamino)-acetate tert-butyl ester 
• 1266244-68-1 C₁₁H₁₆ClN₃O₃ 
• 14628-57-0 4-chloro-5-methoxy-2-methyl-2H-pyridazin-3-one 
• 933-76-6 4,5-dichloro-2-methyl-3(2H)-pyridazinone 

Downstream Products

• 1266245-57-1 4-(2-chloro-5-trifluoromethyl-phenoxy)-piperidine-1-carboxylic acid (2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-amide 
• 1266245-05-9 4-{2-[4-(5-fluoro-2-trifluoromethyl-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-2-methyl-2H-pyridazin-3-one 
• 1266245-06-0 4-{2-[4-(3-fluoro-5-trifluoromethyl-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-2-methyl-2H-pyridazin-3-one 
• 127755-60-6 5-(2-bromobenzamido)-1-methyl-6-pyridazone 

Relevant academic research and scientific papers

An efficient and practical method for the synthesis of 1-(2,6- difluorobenzoyl)-3-(2-alkyl-3-oxopyridazin-4-yl)ureas as potential chitin synthesis inhibitors

A mild and efficient method for the synthesis of 4-amino-3(2H)- pyridazinones from their corresponding 4,5-dichloropyridazinones under microwave-assisted conditions is described. A series of novel chitin synthesis inhibitors, benzoylphenylureas containing

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.

DERIVATIVES OF 2H PYRIDAZIN- 3 -ONES, THEIR PREPARATION AND THEIR USE AS SCD-1 INHIBITORS

The present invention concerns compounds of general formula (I) characterized in that (formula 1) wherein, in particular: -R1 represents one or more groups such as: trif luoromethyl, halogen such as F, C1, -when n=m=1, W represents CH then Y represents oxygen, -U represents: ? either - (C=O) CH2NH- and is branched at position 4 of pyridazinone, then R2 represents H, ? or -(C=O)NH- and U is branched at positions (4), (5) or (6) of pyridazinone, then R2 represents H, - R3 represents a hydrogen or methyl and the addition salts with pharmaceutically acceptable bases and acids and the different isomers, and their mixtures in any proportion for use as SCD-1 enyzme inhibitors for the treatment of obesitz, tzpe-2 diabetes and lipid disorders.

5-amino-6-pyridazone derivatives, their preparation and herbicidal mixtures containing these derivatives

5-Amino-6-pyridazones of the general formulae Ia and Ib STR1 where R1 is C1 -C4 -alkyl which may carry up to three halogen atoms, R2 is C1 -C4 -alkyl or C3 -C6 -alkeny