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Usage

Uses

Used in Pharmaceutical Industry:
7,8-Dihydro-2,3-bis(4-methylphenyl)pyrido[2,3-b]pyrazine-5(6H)-heptanoic acid is used as a potential pharmaceutical candidate for various applications due to its unique structure and properties. Its specific uses and effects, however, require further research to fully understand its potential in the development of new drugs or therapies.

Upstream product

• 91243-58-2 7-ethyloxyheptanoic acid ethyl ester 
• 1356332-28-9 2,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine 
• 1356332-88-1 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid ethyl ester 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 3990-05-4 ethyl 6-formylhexanoate 
• 452-58-4 2,3-Diaminopyridine 

Downstream Products

• 1356332-89-2 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid mesylate 
• 1447673-35-9 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid xinafoate 
• 1447673-34-8 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid sulfate 
• 1447673-36-0 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid sodium salt 
• 1447673-37-1 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid hydrochloride 
• 1447450-42-1 3-(5-(6-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)hexyl)-1H-tetrazol-1-yl)propanenitrile 
• 1447450-09-0 5-(6-(1H-tetrazol-5-yl)hexyl)-2,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine 
• 1447450-41-0 N-(2-cyanoethyl)-7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanamide 
• 1447305-05-6 N-(benzylsulfonyl)-7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanamide 

Relevant academic research and scientific papers

Ip receptor agonist heterocyclic compounds

The present invention provides heterocyclic derivatives which activate the IP receptor. Activating the IP receptor signaling pathway is useful to treat many forms of PAH, pulmonary fibrosis and exert beneficial effects in fibrotic conditions of various or

SALTS OF AN IP RECEPTOR AGONIST

The invention relates to salts of (7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)- yl)heptanoic acid which are useful for treating diseases affected by the activation of the IP receptor, pharmaceutical compositions that contain the salts and processes for preparing the salts are also described.

FUSED PIPERIDINES AS IP RECEPTOR AGONISTS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION (PAH) AND RELATED DISORDERS

The present invention provides heterocyclic derivatives which activate the IP receptor, processes for preparing them, pharmaceutical compositions comprising said derivatives and uses thereof. Activating the IP receptor signaling pathway is useful to treat many forms of PAH, pulmonary fibrosis and exert beneficial effects in fibrotic conditions of various organs in animal models and in patients. Formula (I):

IP RECEPTOR AGONIST HETEROCYCLIC COMPOUNDS

The present invention provides heterocyclic derivatives which activate the IP receptor. Activating the IP receptor signaling pathway is useful to treat many forms of PAH, pulmonary fibrosis and exert beneficial effects in fibrotic conditions of various organs in animal models and in patients. Pharmaceutical compositions comprising such derivatives are also encompassed.