1356332-28-9

Basic information

• Product Name: 2,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine
• Synonyms: 2,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine;Pyrido[2,3-b]pyrazine, 5,6,7,8-tetrahydro-2,3-bis(4-methylphenyl)-;EOS-60892
• CAS NO: 1356332-28-9
• Molecular Formula: C₂₁H₂₁N₃
• Molecular Weight: 315.41154
• Mol File: 1356332-28-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine(1356332-28-9)
• EPA Substance Registry System: 2,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine(1356332-28-9)

Safety Data

• Hazardous Substances Data: 1356332-28-9(Hazardous Substances Data)

Usage

General Description

2,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine is a chemical compound with a complex structure. It belongs to the class of pyrido[2,3-b]pyrazine derivatives and is characterized by the presence of four p-tolyl groups and a tetrahydropyrido ring system. 2,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine has potential applications in medicinal chemistry and pharmaceutical research due to its unique structure and potential biological activities. It may also be used as a building block in organic synthesis to create other related compounds with desired properties. However, this particular compound may also have hazardous effects and should be handled with caution in laboratory settings.

Upstream product

• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 452-58-4 2,3-Diaminopyridine 

Downstream Products

• 1356332-66-5 tert-butyl 2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazine-5(6H)-carboxylate 
• 1356332-88-1 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid ethyl ester 
• 1356332-03-0 7-(8-hydroxy-2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid 
• 1356332-04-1 7-(8-hydroxy-2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid 
• 1356332-10-9 7-(8-hydroxy-2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid 
• 1356333-04-4 ethyl 7-(8-acetoxy-2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoate 
• 1356332-65-4 2,3‐bis(4‐methylphenyl)‐5H,6H,7H,8H‐pyrido[2,3‐b]pyrazin‐8‐yl acetate 
• 1356332-14-3 4-(2-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)ethylamino)-4-oxobutanoic acid 
• 1356333-17-9 2-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)ethanamine 
• 1356333-18-0 ethyl 4-(2-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)ethylamino)-4-oxobutanoate 
• 1356332-67-6 tert-butyl 8-bromo-2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazine-5(6H)-carboxylate 
• 1356332-68-7 tert-butyl 8-acetoxy-2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazine-5(6H)-carboxylate 
• 1356331-63-9 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid 
• 1356332-89-2 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid mesylate 

Relevant articles and documents

FUSED PIPERIDINES AS IP RECEPTOR AGONISTS FOR THE TREATMENT OF PAH AND RELATED DISORDERS

The present invention provides heterocyclic derivatives which activate the IP receptor. Activating the IP receptor signaling pathway is useful to treat many forms of PAH, pulmonary fibrosis and exert beneficial effects in fibrotic conditions of various organs in animal models and in patients. Pharmaceutical compositions comprising such derivatives are also encompassed.

SALTS OF AN IP RECEPTOR AGONIST

The invention relates to salts of (7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)- yl)heptanoic acid which are useful for treating diseases affected by the activation of the IP receptor, pharmaceutical compositions that contain the salts and processes for preparing the salts are also described.