135641-70-2 Usage
General Description
Methyl3-(4-chlorophenyl)-1H-pyrazole-4-carboxylate is a chemical compound with the molecular formula C11H9ClN2O2. It is a pyrazole derivative that contains a methyl ester functional group and a 4-chlorophenyl group. Methyl3-(4-chlorophenyl)-1H-pyrazole-4-carboxylate has potential applications in the field of medicinal chemistry, particularly in the development of pharmaceuticals. It may also be used as an intermediate in the synthesis of other organic compounds. Methyl3-(4-chlorophenyl)-1H-pyrazole-4-carboxylate should be handled and used with proper safety precautions and in accordance with established chemical handling guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 135641-70-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,6,4 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 135641-70:
(8*1)+(7*3)+(6*5)+(5*6)+(4*4)+(3*1)+(2*7)+(1*0)=122
122 % 10 = 2
So 135641-70-2 is a valid CAS Registry Number.
135641-70-2Relevant articles and documents
Effect of Electron-withdrawing Groups on the Thermal Ring Opening of 3H-Pyrazoles to Diazoalkenes
Nakano, Yoshihiko,Ilamaguchi, Masashi,Nagai, Toshikazu
, p. 1701 - 1757 (2007/10/02)
3-Cyano-3H-pyrazoles, bearing a cyano, a p-chlorophenyl, or a p-chlorobenzyl group at C-3, generated from elimination reaction of the corresponding dihydropyrazoles with a leaving group such as a chlorine or p-chlorobenzoyloxy group, gave diazolkene derivatives, resulting from the ring-opening of the 3H-pyrazoles.However, 3-methoxycarbonyl-3H-pyrazoles bearing a methoxycarbonyl, a p-chlorophenyl, or p-chlorobenzyl group at C-3, prepared in a similar manner, gave mainly 1-methoxycarbonyl-1H-pyrazole derivatives, resulting from migration of the 3-methoxycarbonyl group to the adjacent nitrogen within the generated 3H-pyrazoles.Treatment of 3H-pyrazoles (8a and 29b) and 5-substituted 1-methoxycarbonyl-1H-pyrazoles (10a and 31b) with triethylamine gave 3-substituted 1-methoxycarbonyl-1H-pyrazoles, resulting from migration of the methoxycarbonyl group to the remote nitrogen.