135641-70-2 Usage
Uses
Used in Medicinal Chemistry:
Methyl3-(4-chlorophenyl)-1H-pyrazole-4-carboxylate is used as a pharmaceutical intermediate for the development of new drugs. Its unique structure and functional groups contribute to its potential as a building block in the synthesis of various organic compounds with therapeutic applications.
Used in Pharmaceutical Development:
In the pharmaceutical industry, Methyl3-(4-chlorophenyl)-1H-pyrazole-4-carboxylate is utilized as a key component in the creation of novel medications. Its presence in the molecular structure of these drugs can influence their pharmacological properties, such as potency, selectivity, and bioavailability, making it a valuable asset in drug discovery and design.
Used in Organic Synthesis:
Methyl3-(4-chlorophenyl)-1H-pyrazole-4-carboxylate is employed as an intermediate in the synthesis of other organic compounds. Its versatile chemical structure allows for further functionalization and modification, enabling the production of a wide range of chemical entities with diverse applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 135641-70-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,6,4 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 135641-70:
(8*1)+(7*3)+(6*5)+(5*6)+(4*4)+(3*1)+(2*7)+(1*0)=122
122 % 10 = 2
So 135641-70-2 is a valid CAS Registry Number.
135641-70-2Relevant articles and documents
Effect of Electron-withdrawing Groups on the Thermal Ring Opening of 3H-Pyrazoles to Diazoalkenes
Nakano, Yoshihiko,Ilamaguchi, Masashi,Nagai, Toshikazu
, p. 1701 - 1757 (2007/10/02)
3-Cyano-3H-pyrazoles, bearing a cyano, a p-chlorophenyl, or a p-chlorobenzyl group at C-3, generated from elimination reaction of the corresponding dihydropyrazoles with a leaving group such as a chlorine or p-chlorobenzoyloxy group, gave diazolkene derivatives, resulting from the ring-opening of the 3H-pyrazoles.However, 3-methoxycarbonyl-3H-pyrazoles bearing a methoxycarbonyl, a p-chlorophenyl, or p-chlorobenzyl group at C-3, prepared in a similar manner, gave mainly 1-methoxycarbonyl-1H-pyrazole derivatives, resulting from migration of the 3-methoxycarbonyl group to the adjacent nitrogen within the generated 3H-pyrazoles.Treatment of 3H-pyrazoles (8a and 29b) and 5-substituted 1-methoxycarbonyl-1H-pyrazoles (10a and 31b) with triethylamine gave 3-substituted 1-methoxycarbonyl-1H-pyrazoles, resulting from migration of the methoxycarbonyl group to the remote nitrogen.
