135641-91-7

Usage

Uses

Used in Pharmaceutical Industry:
3-(4-Chlorophenyl)-1H-pyrazole-4-carboxylic acid is used as a key intermediate in the synthesis of pharmaceuticals for its potential to enhance the biological activity of the resulting compounds. Its unique structure allows for the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-(4-Chlorophenyl)-1H-pyrazole-4-carboxylic acid is utilized as a precursor in the creation of agrochemicals, contributing to the formulation of pesticides and other products that protect crops and enhance agricultural yields.
Used in Drug Discovery and Development:
3-(4-Chlorophenyl)-1H-pyrazole-4-carboxylic acid is employed as a target molecule in drug discovery and development efforts. Its potential anti-inflammatory and antifungal properties make it a promising candidate for the creation of new therapeutic agents to combat various diseases and infections.
Used in Research and Development of Biologically Active Compounds:
3-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID is also used in research settings to explore its potential as a building block for the development of biologically active compounds. Its unique structure and functional groups make it an interesting subject for scientific investigation, potentially leading to breakthroughs in medicinal chemistry.

InChI:InChI=1/C10H7ClN2O2/c11-7-3-1-6(2-4-7)9-8(10(14)15)5-12-13-9/h1-5H,(H,12,13)(H,14,15)

Upstream product

• 7575-74-8 p-chloroacetophenone semicarbazone 
• 109842-38-8 dimethyl 2-(4-chlorophenyl)maleate 
• 99-91-2 para-chloroacetophenone 
• 350997-67-0 3-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde 

Downstream Products

• 135641-70-2 3-p-chlorophenyl-4-methoxycarbonyl-1H-pyrazole 
• 1347063-14-2 3-propyl-6-(3-(4-chlorophenyl)-1H-pyrazol-4-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 1347063-02-8 3-ethyl-6-(3-(4-chlorophenyl)-1H-pyrazol-4-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 1251922-46-9 2-[3-(4-chlorophenyl)-1H-pyrazol-4-yl]-5-[(2-naphthyloxy)methyl][1,2,4]-triazolo[3,4-b][1,3,4]thiadiazole 

Relevant academic research and scientific papers

Synthesis and anti-inflammatory evaluation of some new 3,6-disubstituted-1, 2,4-triazolo-[3,4-b]-1,3,4-thiadiazoles bearing pyrazole moiety

In the present study, a new series of 3,6-disubstituted- 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazoles (4aj) have been synthesized by condensing 3-substituted-4-amino-5- mercapto-1,2,4-triazoles (1a-b) with various 3-substitutedpyrazole- 4-carboxylic acids (3

Synthesis, characterization, antioxidant, and anticancer studies of 6-[3-(4-chlorophenyl)-1H-pyrazol-4-yl]-3-[(2-naphthyloxy) methyl][1,2,4] triazolo[3,4-b][1,3,4]thiadiazole in HepG2 cell lines

Triazolo- thiadiazoles exhibit a variety of pharmacological properties, due to their cytotoxicity. In continuation of a previous study on triazolo-thiadiazoles, the authors have synthesized a new thiadiazole, 6-[3-(4-chlorophenyl)- 1-H-pyrazol-4-yl]-3-[(2

Synthesis of 3-substituted arylpyrazole-4-carboxylic acids

A method was suggested for preparing previously unknown 3-aryl-substituted pyrazole-4-carboxylic acids, involving Vilsmeier formylation of semicarbazones of 26 available mono- and disubstituted acetophenones and 2-acetylthiophene followed by oxidation of

Effect of Electron-withdrawing Groups on the Thermal Ring Opening of 3H-Pyrazoles to Diazoalkenes

3-Cyano-3H-pyrazoles, bearing a cyano, a p-chlorophenyl, or a p-chlorobenzyl group at C-3, generated from elimination reaction of the corresponding dihydropyrazoles with a leaving group such as a chlorine or p-chlorobenzoyloxy group, gave diazolkene derivatives, resulting from the ring-opening of the 3H-pyrazoles.However, 3-methoxycarbonyl-3H-pyrazoles bearing a methoxycarbonyl, a p-chlorophenyl, or p-chlorobenzyl group at C-3, prepared in a similar manner, gave mainly 1-methoxycarbonyl-1H-pyrazole derivatives, resulting from migration of the 3-methoxycarbonyl group to the adjacent nitrogen within the generated 3H-pyrazoles.Treatment of 3H-pyrazoles (8a and 29b) and 5-substituted 1-methoxycarbonyl-1H-pyrazoles (10a and 31b) with triethylamine gave 3-substituted 1-methoxycarbonyl-1H-pyrazoles, resulting from migration of the methoxycarbonyl group to the remote nitrogen.