1356486-29-7Relevant academic research and scientific papers
Synthesis of trifluoromethylated acetylenes via copper-catalyzed trifluoromethylation of alkynyltrifluoroborates
Zheng, Huidong,Huang, Yuanyuan,Wang, Zhiwei,Li, Huaifeng,Huang, Kuo-Wei,Yuan, Yaofeng,Weng, Zhiqiang
, p. 6646 - 6649 (2012)
A new method for the synthesis of trifluoromethylated acetylenes is developed which involves the copper-catalyzed trifluoromethylation of alkynyltrifluoroborates with an electrophilic trifluoromethylating reagent. This method offers significant advantages such as efficiency and mild and base-free reaction conditions. A plausible mechanism is proposed.
An improved copper-mediated oxidative trifluoromethylation of terminal alkynes
Zhang, Ke,Qiu, Xiao-Long,Huang, Yangen,Qing, Feng-Ling
supporting information; experimental part, p. 58 - 61 (2012/01/15)
An improved method for the efficient copper-mediated trifluoromethylation of terminal alkynes has been developed. This protocol highlights the convenient access to a variety of aryl-substituted trifluoromethylated alkynes by oxidative trifluoromethylation
