1356584-75-2

Upstream product

• 1356584-67-2 [(R)-1-(3,5-dichlorophenylcarbamoyl)[2,2,2-⁽²⁾H₃]ethyl]carbamic acid tert-butyl ester 
• 1356584-69-4 (R)-2-amino-N-(3,5-dichlorophenyl)[3,3,3-⁽²⁾H]propionamide 
• 1356584-71-8 (2S,5R)-2-(tert-butyl)-3-(3,5-dichlorophenyl)-5-([⁽²⁾H₃]methyl)imidazolidin-4-one 
• 1356584-73-0 (2S,5R)-2-(tert-butyl)-3-(3,5-dichlorophenyl)-5-[⁽²⁾H₃]methyl-1-(2,2,2-trifluoroacetyl)imidazolidin-4-one 
• 50824-05-0 4-trifluoromethoxybenzyl bromide 
• 630-19-3 pivalaldehyde 

Downstream Products

• 1356584-80-9 tert-butyl N-[2-[[(1R)-2-(3,5-dichloroanilino)-1-[⁽²⁾H₃]methyl-2-oxo-1-[[4-(trifluoromethoxy)phenyl]methyl]ethyl]amino]-2-oxo[⁽¹³⁾C₂]ethyl]carbamate 
• 1356584-77-4 (2R)-2-amino-N-(3,5-dichlorophenyl)-2-[⁽²⁾H₃]methyl-3-[4-(trifluoromethoxy)phenyl]propanamide 

Relevant academic research and scientific papers

Synthesis of a highly potent leukocyte function-associated antigen-1 antagonist and its metabolite labeled with stable isotopes and carbon-14, part 2

(S)-2-[(R)-7-(3,5-Dichlorophenyl)-5-methyl-6-oxo-5-(4- trifluoromethoxybenzyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino] -proprionamide (1), a potent lymphocyte function-associated antigen-1 antagonist and its sulfonamide metabolite (2) labe