135684-35-4Relevant academic research and scientific papers
SAR and LC/MS studies of β-lactamic inhibitors of human fatty acid amide hydrolase (h FAAH): Evidence of a nonhydrolytic process
Feledziak, Marion,Muccioli, Giulio G.,Lambert, Didier M.,Marchand-Brynaert, Jacqueline
supporting information; experimental part, p. 6812 - 6823 (2011/12/04)
The endocannabinoid hydrolyzing enzyme FAAH uses a nonclassical catalytic triad (namely, Ser-Ser-Lys instead of Ser-Asp-His) to cleave its endogenous substrates. Because inhibiting FAAH has a clear therapeutic potential, we previously developed β-lactam-t
Enzymatic process for preparing optically active 3-substituted azetidinones
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, (2008/06/13)
Preparation of optically active 3-substituted azetidinones of the formula (I) STR1 in which R1 is a hydroxy-protective group wherein an allylic alcohol of the formula (II) STR2 is acylated, then subjected to asymmetric enzymatic hydrolysis yiel
