135708-73-5

Upstream product

• 902151-30-8 (2S,3R)-2-Benzyloxy-5-hydroxy-3-methoxy-cyclohexanone 
• 6752-48-3 (4aR,6S,8R,8aS)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-ol 
• 126257-19-0 Methyl 2-deoxy-3-O-methyl-6-O-triphenylmethyl-α-D-arabino-hexopyranoside 
• 135708-69-9 (3S,4R,6S)-3-Benzyloxy-4,6-dimethoxy-2-methylene-tetrahydro-pyran 
• 674769-31-4 Benzoic acid (2S,3S,4R)-2-bromomethyl-4,6-dimethoxy-tetrahydro-pyran-3-yl ester 
• 21090-92-6 (2R,4aR,8R,8aS)-6,8-Dimethoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine 
• 135708-69-9 (3S,4R)-3-Benzyloxy-4,6-dimethoxy-2-methylene-tetrahydro-pyran 
• 6752-48-3 methyl 4,6-O-benzylidene-2-deoxy-α,β-D-arabino-hexopyranoside 
• 135708-67-7 (2S,3S,4R)-2-Bromomethyl-4,6-dimethoxy-tetrahydro-pyran-3-ol 
• 100-39-0 benzyl bromide 
• 13145-22-7 methyl 2-deoxy-α-D-glucopyranoside 
• 99371-27-4 Methyl 2-deoxy-3-O-methyl-α-D-arabino-hexopyranoside 
• 6087-40-7 (2R,3S,4R,6S)-3,4-diacetoxy-2-(acetoxymethyl)-6-methoxytetrahydro-2H-pyran 
• 53131-18-3 methyl O⁴,O⁶-(R)-benzylidene-O³-methyl-α-D-arabino-2-deoxy-hexopyranoside 

Downstream Products

• 135708-84-8 (3R,4S,6S,7R)-8-Benzyloxy-4,6-bis-(tert-butyl-dimethyl-silanyloxy)-3,7-dimethyl-octanoic acid (1S,5R,6S)-6-benzyloxy-5-methoxy-cyclohex-2-enyl ester 
• 135708-85-9 C₄₉H₈₄O₇Si₃ 
• 135708-74-6 (1S,5R,6R)-6-Benzyloxy-5-methoxy-cyclohex-2-enol 

Relevant academic research and scientific papers

Novel γ-secretase inhibitors discovered by library screening of in-house synthetic natural product intermediates

Screening of our in-house compound library comprised of intermediates of natural product synthesis projects resulted in discovering two novel γ-secretase inhibitors, which coincidently had similar moieties, that is, cyclohexenone and two aryl groups arran

Synthetic Studies toward Rapamycin: A Solution to a Problem in Chirality Merger through Use of the Ireland Reaction

A program directed toward a total synthesis of rapamycin is described.This paper reports the synthesis of enoate 36, a fragment that would correspond to carbons 28-49 of rapamycin.The two building blocks required to reach 36 were allylic alcohol 5 and aci