1357168-68-3

Basic information

• Product Name: N-[3-(2,5-dimethylbenzyloxy)-4-(N-methanesulfonyl-N-methylamino)phenyl]isoxazole-5-carboxamide
• Synonyms: N-[3-(2,5-dimethylbenzyloxy)-4-(N-methanesulfonyl-N-methylamino)phenyl]isoxazole-5-carboxamide
• CAS NO: 1357168-68-3
• Molecular Weight: 429.497
• Mol File: 1357168-68-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[3-(2,5-dimethylbenzyloxy)-4-(N-methanesulfonyl-N-methylamino)phenyl]isoxazole-5-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(2,5-dimethylbenzyloxy)-4-(N-methanesulfonyl-N-methylamino)phenyl]isoxazole-5-carboxamide(1357168-68-3)
• EPA Substance Registry System: N-[3-(2,5-dimethylbenzyloxy)-4-(N-methanesulfonyl-N-methylamino)phenyl]isoxazole-5-carboxamide(1357168-68-3)

Safety Data

• Hazardous Substances Data: 1357168-68-3(Hazardous Substances Data)

Upstream product

• 121-88-0 5-Nitro-2-aminophenol 
• 824-45-3 2,5-dimethylbenzyl chloride 
• 1021926-19-1 C₁₇H₂₂N₂O₃S 
• 62348-13-4 isooxazole-5-carbonyl chloride 
• 1021926-24-8 C₁₇H₂₀N₂O₇S₂ 
• 930797-71-0 N-[2-(3',6'-dimethyI-benzyloxy)-4-nitrophenyl]-methanesulfonamide 
• 930797-62-9 2-(2,5-dimethylbenzyloxy)-4-nitroaniline 

Relevant articles and documents

From COX-2 inhibitor nimesulide to potent anti-cancer agent: Synthesis, in vitro, in vivo and pharmacokinetic evaluation

Cyclooxygenase-2 (COX-2) inhibitor nimesulide inhibits the proliferation of various types of cancer cells mainly via COX-2 independent mechanisms, which makes it a good lead compound for anti-cancer drug development. In the presented study, a series of ne