1357173-35-3Relevant academic research and scientific papers
Chiral AuI- and AuIII-Isothiourea Complexes: Synthesis, Characterization and Application
Gasperini, Danila,Greenhalgh, Mark D.,Imad, Rehan,Siddiqui, Shezaib,Malik, Anum,Arshad, Fizza,Choudhary, Muhammad Iqbal,Al-Majid, Abdullah M.,Cordes, David B.,Slawin, Alexandra M. Z.,Nolan, Steven P.,Smith, Andrew D.
, p. 1064 - 1075 (2019)
During an investigation into the potential union of Lewis basic isothiourea organocatalysis and gold catalysis, the formation of gold-isothiourea complexes was observed. These novel gold complexes were formed in high yield and were found to be air- and moisture stable. A series of neutral and cationic chiral gold(I) and gold(III) complexes bearing enantiopure isothiourea ligands was therefore synthesized and fully characterized. The steric and electronic properties of the isothiourea ligands was assessed through calculation of their percent buried volume and the synthesis and analysis of novel iridium(I)-isothiourea carbonyl complexes. The novel gold(I)- and gold(III)-isothiourea complexes have been applied in preliminary catalytic and biological studies, and display promising preliminary levels of catalytic activity and potency towards cancerous cell lines and clinically relevant enzymes.
Silver oxide(I) promoted Conia-ene/radical cyclization for a straightforward access to furan derivatives
Ardisson, Janick,Lannou, Marie-Isabelle,Mohamed, Selkti,Sorin, Geoffroy,Yu, Bao
, p. 1374 - 1377 (2022/02/11)
A novel access to fused furan cores using silver oxide(I) has been developed. Mechanistic investigations indicate the involvement of a Conia-ene reaction/radical cyclization for an expedient path to complex furan derivatives. The reaction is broad in scop
