1357178-72-3

Upstream product

• 50-99-7 D-glucose 
• 26597-73-9 1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-ulose 
• 582-52-5 1,2:5,6-diacetone-D-glucose 
• 14267-92-6 1-chloro-4-pentyne 
• 1357178-65-4 1,2-O-isopropylidene-3-C-phenyl-5-azido-α-D-ribofuranose 
• 1357178-64-3 1,2-O-isopropylidene-3-C-phenyl-5-O-tosyl-α-D-ribofuranose 
• 237412-43-0 1,2-O-isopropylidene-3-C-phenyl-α-D-ribofuranose 
• 1043894-82-1 C₁₄H₁₆O₅ 

Relevant academic research and scientific papers

Synthesis of 1,2,3-triazole glycoconjugates as inhibitors of α-glucosidases

Ten new 1,2,3-triazole glycoconjugates were synthesized from d-glucose and evaluated in in vitro assays for their ability to inhibit the enzyme α-glucosidase. Most of the compounds had low activity or were inactive when compared with acarbose. However, the derivative 1,2-O-isopropylidene-3- phenyl-5-(4-phenyl-1H-1,2,3-triazole-1-yl)-α-d-ribofuranose (19i) possessed activity comparable with the standard drug. The influence of the phenyl group on carbon 3 of the carbohydrate framework is discussed.