1357588-08-9

Basic information

• Product Name: 4-[3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-[3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 1357588-08-9
• Molecular Weight: 696.75
• Mol File: 1357588-08-9.mol

Chemical Properties

• CAS DataBase Reference: 4-[3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester(1357588-08-9)
• EPA Substance Registry System: 4-[3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester(1357588-08-9)

Safety Data

• Hazardous Substances Data: 1357588-08-9(Hazardous Substances Data)

Upstream product

• 26120-86-5 2,5-difluorobenzenesulfonyl chloride 
• 319474-34-5 4-iodo-1H-pyrrolo[2,3-b]pyridine 
• 1357588-07-8 4-[3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyrazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 58534-95-5 3-bromo-2-fluorobenzenamine 
• 1357587-46-2 N-(3-bromo-2-fluorophenyl)-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 
• 1357587-47-3 2,5-difluoro-N-{2-fluoro-3-[2-(tetrahydropyran-2-yl)-2H-pyrazol-3-yl]phenyl}-N-methoxymethylbenzenesulfonamide 
• 1357587-48-4 2,5-difluoro-N-[2-fluoro-3-(2H-pyrazol-3-yl)-phenyl]-N-methoxymethylbenzenesulfonamide 
• 1357587-65-5 4-(4-bromo-3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}pyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 
• 1357587-49-5 N-[3-(4-bromo-1H-pyrazol-3-yl)-2-fluorophenyl]-2,5-difluoro-N-methoxymethylbenzenesulfonamide 
• 1357587-45-1 N-(3-bromo-2-fluorophenyl)-2,5-difluorobenzenesulfonamide 

Downstream Products

• 1357587-25-7 2,5-difluoro-N-{2-fluoro-3-[1-(1-methylpiperidin-4-yl)-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}benzenesulfonamide 

Relevant articles and documents

DERIVATIVES OF PYRAZOLOPHENYL-BENZENESULFONAMIDE COMPOUNDS AND USE THEREOF AS ANTITUMOR AGENTS

Substituted pyrazolophenyl-benzenesulfonamide compounds of formula (I) are described, wherein m, R1, R2, R3, and R4 are defined in the description, which modulate the activity of protein kinases, These compounds find utility in treating diseases caused by deregulated protein kinase activity, such as cancer and cell proliferative disorders.