135840-23-2

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 114934-98-4 2,5-di-O-benzyl-1,6-bis-O-tert-butyldiphenylsilanyl-D-mannitol 
• 17618-04-1 2,5-di-O-benzyl-D-mannitol 
• 18292-38-1 2-methallyltrimethylsilane 
• 122598-86-1 2-O-Benzyl-3-O-(tert-butyldiphenylsilyl)glyceraldehyde 

Downstream Products

• 135840-25-4 (2R,3S)-2-O-benzyl-1-O-tert-butyldiphenylsilyl-3-O,5-dimethyl-5-hexene-1,2,3-triol 
• 186406-69-9 ((E)-(2R,6S,8R,9R,10S,12R)-2-Allyl-9,13-bis-benzyloxy-8,10-dimethoxy-4,6,12-trimethyl-tridec-3-enyloxy)-tert-butyl-dimethyl-silane 
• 186406-68-8 (E)-(2R,4S,5R,6R,8S,12R)-1,5-Bis-benzyloxy-12-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxy-2,8,10-trimethyl-pentadeca-10,14-dien-6-ol 
• 186406-65-5 (2R,4S,5R)-6-(tert-Butyl-diphenyl-silanyloxy)-4-methoxy-2-methyl-hexane-1,5-diol 
• 137963-56-5 (2R,4S,5R)-5-(tert-butyldiphenylsilyl)oxymethyl-4-methoxy-2-methyl-5-pentanolide 
• 137963-57-6 (2S,4S,5R)-5-(tert-butyldiphenylsilyl)oxymethyl-4-methoxy-2-methyl-5-pentanolide 
• 135840-26-5 (2R,4S,5R)-5-benzyloxy-6-(tert-butyldiphenylsilyl)oxy-4-methoxy-2-methyl-1-hexanol 
• 135912-31-1 (2S,4S,5R)-5-benzyloxy-6-(tert-butyldiphenylsilyl)oxy-4-methoxy-2-methyl-1-hexanol 
• 186406-67-7 (E)-(2R,4S,5S,8S,12R)-7-Benzenesulfonyl-1,5-bis-benzyloxy-12-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxy-2,8,10-trimethyl-pentadeca-10,14-dien-6-one 
• 186406-66-6 (E)-(2R,4S,5R,8S,12R)-7-Benzenesulfonyl-1,5-bis-benzyloxy-12-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxy-2,8,10-trimethyl-pentadeca-10,14-dien-6-ol 
• 135840-28-7 (2R,4S,5S,8S,10E,12R)-1,5-dibenzyloxy-12-(tert-butyldimethylsilyl)oxymethyl-4-methoxy-2,8,10-trimethyl-10,14-pentadecadien-6-one 
• 186406-60-0 (4R,5E,8S,10S,11R,12S,14R)-11,15-dibenzyloxy-4-(tert-butyldimethylsilyl)oxymethyl-10,12-dimethoxy-6,8,14-trimethyl-1,5-pentadecadiene 
• 135840-29-8 (2R,4S,5R,6S,8S,10E,12R)-1,5-dibenzyloxy-12-(tert-butyldimethylsilyl)oxymethyl-4-methoxy-2,8,10-trimethyl-10,14-pentadecadien-6-ol 
• 186406-58-6 (2R,3S,5R)-2,6-dibenzyloxy-1-(tert-butyldiphenylsilyl)oxy-3-methoxy-5-methylhexane 

Relevant academic research and scientific papers

Stereocontrolled synthesis of C10-C22 fragment of the immunosuppressant FK 506. An occurrence of complementary stereoselectivity in the C15 ketone reduction

The stereoselective syntheses of the C10-C22 fragment 2a and its C15-epimer 2b of the immunosuppressant FK 506 1 have been carried out through convergent coupling of the sulfone 3, which could be constructed by highly stereocontrolled ester-enolate Claise

A Synthesis of C1-C22 Fragment of the Immunosuppressant FK 506. Stereoselective Construction of (E)-Trisubstituted Double Bond (C19-C20) via Ester-enolate Claisen Rearrangement

An ene-ester 5 prepared from L-malic acid was subjected to the ester-enolate Claisen rearrangement under Ireland's condition to give stereoselectively C16-C22 fragment 11 containing (E)-trisubstituted double bond which was further advanced to C1-C22 fragm