13591-60-1Relevant academic research and scientific papers
A novel efficient three-component one-pot synthesis of 1,3-diazabicyclo[3. 1.0]hex-3-ene system under microwave irradiation
Risitano, Francesco,Grassi, Giovanni,Foti, Francesco,Moraci, Sonia
, p. 1633 - 1635 (2005)
Bridgehead aziridines 3 were synthesized in high yields and excellent diastereocontrol by a three-component reaction of an aldehyde, phenacyl chloride and ammonium acetate in acetic acid using microwave irradiation. Georg Thieme Verlag Stuttgart.
An improved diastereoselective synthesis of spiroazoles using multicomponent domino transformations
Altieri, Elisa,Cordaro, Massimiliano,Grassi, Giovanni,Risitano, Francesco,Scala, Angela
experimental part, p. 2106 - 2108 (2010/10/03)
Spiroisoxazole and spiropyrazole derivatives were obtained in a four-component reaction of active isoxazol- or pyrazol-5-ones with aromatic aldehydes, phenacyl chloride and AcOH-AcONH4 mixture. The reaction sequence is highly chemo- and diastereoselective affording good yields of spiroisoxazoles in refluxing ethanol, while efficient formation of spiropyrazoles is closely related to the use of a microwave-assisted protocol.
Structure investigation of bridgehead aziridine: Synthesis, theoretical, and crystallographic study of 2,4,6-triphenyl-1,3-diazabicyclo[3.1.0]hex-3-ene
Bruno, Giuseppe,Nicolo, Francesco,Rotondo, Archimede,Risitano, Francesco,Grassi, Giovanni,Foti, Francesco
, p. 190 - 200 (2007/10/03)
A one-pot three-component procedure to efficiently create the 1,3-diazabicyclo[3.1.0]hex-3-ene system is reported. The molecular structure of 2,4,6-triphenyl-1,3-diazabicyclo[3.1.0]hex-3-ene (3) was studied by X-ray diffraction and compared to ab initio a
AZIRIDINYL KETONES AND THEIR CYCLIC ANILS. 10. 2,4,6-TRIARYL-1,3-DIAZABICYCLOHEX-3-ENES
Orlov, V. D.,Kaluski, Z.,Figas, E.,Vorob'eva, N. P.,Bakumenko, A. I.,Yaremenko, F. G.
, p. 849 - 854 (2007/10/02)
2,4,6-Triaryl-1,3-diazabicyclohex-3-enes were prepared by the reaction of α,β-dibromochalcones with aromatic aldehydes and ammonia.The exo- and endo-isomers were isolated and characterized.X-ray structural analysis of the endo-6-(4-nitrophenyl)-2,4
