135941-84-3 Usage
Uses
Used in Pharmaceutical Industry:
Boc-L-aspartic acid 4-Methyl ester dicyclohexylaMMoniuM salt is used as a key intermediate in the synthesis of isoxazoline glycoprotein IIb/IIIa antagonists. These antagonists are important in the development of antiplatelet drugs, which are crucial for the treatment of various cardiovascular diseases, such as acute coronary syndrome, myocardial infarction, and stroke.
Additionally, Boc-L-aspartic acid 4-Methyl ester dicyclohexylaMMoniuM salt is used as a starting material for the synthesis of glutamic acid analogs. These analogs have been identified as potent inhibitors of leukotriene A4 hydrolase (LTA4H), an enzyme involved in the production of leukotrienes, which are inflammatory mediators. Inhibiting LTA4H can help in the development of anti-inflammatory drugs for the treatment of conditions such as asthma, rheumatoid arthritis, and inflammatory bowel disease.
Check Digit Verification of cas no
The CAS Registry Mumber 135941-84-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,9,4 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 135941-84:
(8*1)+(7*3)+(6*5)+(5*9)+(4*4)+(3*1)+(2*8)+(1*4)=143
143 % 10 = 3
So 135941-84-3 is a valid CAS Registry Number.
135941-84-3Relevant academic research and scientific papers
Improved synthesis of L-homoserine derivatives from L-aspartic acid
Uzar
, p. 526 - 528 (2007/10/02)
N-Alkoxycarbonyl-L-homoserine lactones (α-alkoxycarbonyl-amino-γ-butyrolactones) were prepared by selective esterification of L-aspartatic acid followed by N-protection, precipitation of the dicyclohexylammonium salts, chemoselective reduction with lithium borohydride, and cyclization to the corresponding γ-lactones during isolation.
