135944-05-7 Usage
Chemical Properties
White solid
Uses
Fmoc-alpha-methyl-L-phenylalanine is a useful reagent for the synthesis of peptidic partial agonists of human neuromedin U receptor with enhanced serum stability.
Check Digit Verification of cas no
The CAS Registry Mumber 135944-05-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,9,4 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 135944-05:
(8*1)+(7*3)+(6*5)+(5*9)+(4*4)+(3*4)+(2*0)+(1*5)=137
137 % 10 = 7
So 135944-05-7 is a valid CAS Registry Number.
InChI:InChI=1/C25H23NO4/c1-25(23(27)28,15-17-9-3-2-4-10-17)26-24(29)30-16-22-20-13-7-5-11-18(20)19-12-6-8-14-21(19)22/h2-14,22H,15-16H2,1H3,(H,26,29)(H,27,28)/t25-/m0/s1
135944-05-7Relevant articles and documents
Thrombin receptor-activating peptides (TRAPs): Investigation of bioactive conformations via structure-activity, spectroscopic, and computational studies
Ceruso, Marco A.,McComsey, David F.,Leo, Gregory C.,Andrade-Gordon, Patricia,Addo, Michael F.,Scarborough, Robert M.,Oksenberg, Donna,Maryanoff, Bruce E.
, p. 2353 - 2371 (2007/10/03)
The thrombin receptor (PAR-1) is an unusual transmembrane G-protein coupled receptor in that it is activated by serine protease cleavage of its extracellular N-terminus to expose an agonist peptide ligand, which is tethered to the receptor itself. Synthet