FMOC-ALPHA-METHYL-L-PHE

Base Information

Chemical Name:FMOC-ALPHA-METHYL-L-PHE
CAS No.:135944-05-7
Molecular Formula:C25H23NO4
Molecular Weight:401.462
Hs Code.:2924299090
Mol file:135944-05-7.mol

Synonyms:FMOC-(S)-2-AMINO-2-METHYL-3-PHENYLPROPANOIC ACID;FMOC-ALPHA-BENZYL-L-ALA;FMOC-ALPHA-ME-PHE-OH;FMOC-ALPHA-METHYL-L-PHE;FMOC-ALPHA-METHYL-L-PHENYLALANINE;FMOC-ALPHA-METHYL-PHENYLALANINE;Fmoc-á-Me-Phe-OH

Suppliers and Price of FMOC-ALPHA-METHYL-L-PHE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-alpha-methyl-L-phenylalanine
500mg
$ 382.00

TRC
Fmoc-α-methyl-L-phenylalanine
100mg
$ 60.00

Matrix Scientific
Fmoc-alpha-methyl-L-phenylalanine
250mg
$ 251.00

Matrix Scientific
Fmoc-alpha-methyl-L-phenylalanine
1g
$ 681.00

Crysdot
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methyl-3-phenylpropanoicacid 95+%
5g
$ 515.00

Crysdot
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methyl-3-phenylpropanoicacid 95+%
10g
$ 995.00

ChemSupplyAustralia
(S)-N-Fmoc-α-Methylphenylalanine.3/2H2O, 98%
5 g
$ 990.00

ChemSupplyAustralia
(S)-N-Fmoc-α-Methylphenylalanine.3/2H2O, 98%
1 g
$ 330.00

ChemPep
Fmoc-α-Me-Phe-OH
1g
$ 200.00

ChemPep
Fmoc-α-Me-Phe-OH
5g
$ 650.00

Total 36 raw suppliers

Chemical Property of FMOC-ALPHA-METHYL-L-PHE

Chemical Property:

Vapor Pressure:2.71E-16mmHg at 25°C
Refractive Index:1.625
Boiling Point:621.2°C at 760 mmHg
PKA:3.81±0.11(Predicted)
Flash Point:329.5°C
PSA：75.63000
Density:1.256g/cm³
LogP:5.00200
Storage Temp.:Store at 0-5°C
Solubility.:Chloroform (Slightly), DMF (Slightly), Methanol (Slightly)

Purity/Quality:

≥98%, ^*data from raw suppliers

Fmoc-alpha-methyl-L-phenylalanine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38-40-67
Safety Statements: 23-24/25-36/37

MSDS Files:: SDS file from LookChem

Useful:

Uses Fmoc-alpha-methyl-L-phenylalanine is a useful reagent for the synthesis of peptidic partial agonists of human neuromedin U receptor with enhanced serum stability.

Technology Process of FMOC-ALPHA-METHYL-L-PHE

There total 1 articles about FMOC-ALPHA-METHYL-L-PHE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 23239-35-2
(S)-2-amino-2-methyl-3-phenylpropanoic acid

: 135944-05-7,152436-04-9
(2S)-2-[9H-fluorene-9-ylmethoxycarbonylamino]-2-methyl-3-phenylpropanoic acid

Guidance literature:: With sodium carbonate; In 1,4-dioxane; water; at 0 - 23 ℃;
DOI:10.1016/S0968-0896(99)00180-7

Reference yield: 100.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 135944-05-7,152436-04-9
(2S)-2-[9H-fluorene-9-ylmethoxycarbonylamino]-2-methyl-3-phenylpropanoic acid

: C₂₆H₂₃NO₄

Guidance literature:: With camphor-10-sulfonic acid; In toluene; at 85 ℃; for 4h;

Reference yield: 53.2%

: 35661-40-6
N-Fmoc L-Phe

: 135944-05-7,152436-04-9
(2S)-2-[9H-fluorene-9-ylmethoxycarbonylamino]-2-methyl-3-phenylpropanoic acid

: 1204418-11-0
Phe-α-Me-Phe-NH2

Guidance literature:: N-Fmoc L-Phe; With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; Rink amide MBHA resin

With piperidine; In N,N-dimethyl-formamide; Rink amide MBHA resin

(2S)-2-[9H-fluorene-9-ylmethoxycarbonylamino]-2-methyl-3-phenylpropanoic acid; Further stages;
DOI:10.1021/jm400209h