135967-47-4

Upstream product

• 63-91-2 L-phenylalanine 
• 123381-13-5 N-Triphenylmethyl-cyclohexylalanine methyl ester 
• 40056-18-6 methyl L-cyclohexylalaninate 
• 27527-05-5 L-cyclohexylalanine 
• 3952-67-8 methyl 3-methyl-2-ketobutanoate 
• 135967-46-3 Dimethyl 3(S)-4-Cyclohexyl-3-(N-triphenylmethyl)amino-2-oxobutylphosphonate 

Downstream Products

• 135967-48-5 (6S)-7-Cyclohexyl-2-methyl-6-(N-triphenylmethyl)-amino-5-oxohept-2-ene-3-oic acid 
• 135967-49-6 (S)-6-Cyclohexyl-2-isopropylidene-4-oxo-5-(trityl-amino)-hexanoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 135967-45-2 (S)-6-Cyclohexylmethyl-3-isopropylidene-piperidine-2,5-dione 
• 142687-80-7 (3S,5S,6S)-6-Cyclohexylmethyl-5-hydroxy-3-isopropylpiperidin-2-one 
• 135967-50-9 (5S,6S)-6-Cyclohexylmethyl-3-isopropylidene-5-hydroxypiperidine-2-one 
• 125816-10-6 <3S-<3α,5β(R^*)>>-5-(2-Cyclohexyl-1-aminoethyl)dihydro-3-isopropyl-2(3H)-furanone 

Relevant academic research and scientific papers

The stereospecific preparation of a hydroxyethylene isostere precursor via a novel piperidine-2,5-dione template

Hydroxyethylene isostere precursor 2 was synthesized by stereochemical manipulation of a novel ketolactam 'template'. The final product was prepared in very high enantiomeric purity, in 23% overall yield from L-phenylalanine.