The stereospecific preparation of a hydroxyethylene isostere precursor via a novel piperidine-2,5-dione template

DOI: 10.1016/S0040-4039(00)79750-4

Source and publish data:

Tetrahedron Letters p. 3623 - 3626 (1991)

Update date:2022-07-30

Topics:

Authors:

Plata Plata

Leanna Leanna

Morton Morton

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Article abstract of DOI:10.1016/S0040-4039(00)79750-4

Hydroxyethylene isostere precursor 2 was synthesized by stereochemical manipulation of a novel ketolactam 'template'. The final product was prepared in very high enantiomeric purity, in 23% overall yield from L-phenylalanine.

Full text of DOI:10.1016/S0040-4039(00)79750-4

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