13605-19-1

Usage

Uses

Used in Pharmaceutical Industry:
2-(3-METHYLPHENOXY)ETHANOL is used as a solvent for the extraction, purification, and formulation of pharmaceuticals. Its ability to dissolve a wide range of substances aids in the development and production of various medications.
Used in Pesticide Industry:
In the pesticide industry, 2-(3-METHYLPHENOXY)ETHANOL is utilized as a solvent to facilitate the extraction and formulation of pesticides, enhancing the effectiveness of these products in agricultural applications.
Used in Chemical Synthesis:
2-(3-METHYLPHENOXY)ETHANOL is used as a reactant in the synthesis of other organic compounds, contributing to the creation of new chemical entities for various applications.
Used in Specialty Chemicals Manufacturing:
It serves as a component in the manufacture of specialty chemicals, where its solvent properties are leveraged to produce unique chemical products with specific uses.
2-(3-METHYLPHENOXY)ETHANOL is considered relatively safe for handling, provided that it is used with appropriate safety measures in place, minimizing health risks associated with its use.

InChI:InChI=1/C8H17NO2/c1-7-5-9(3-4-10)6-8(2)11-7/h7-8,10H,3-6H2,1-2H3

Upstream product

• 75-21-8 oxirane 
• 108-39-4 3-methyl-phenol 
• 1643-15-8 2-(m-tolyloxy)acetic acid 
• 3019-89-4 sodium 3-methylphenoxide 
• 107-07-3 2-chloro-ethanol 
• 1193-18-6 3-methylcyclohexen-2-one 
• 107-21-1 ethylene glycol 
• 540-51-2 2-bromoethanol 

Downstream Products

• 860408-23-7 4-[4-(2-hydroxy-ethoxy)-2-methyl-phenyl]-4-oxo-butyric acid 
• 31432-79-8 carbamic acid-(2-m-tolyloxy-ethyl ester) 
• 62644-00-2 β-m-Tolyloxyaethyl-m-tolylcarbamat 
• 62643-89-4 β-m-Tolyloxyaethyl-o-tolylcarbamat 
• 62643-88-3 β-o-Tolyloxyaethyl-o-tolylcarbamat 
• 136199-52-5 Sulfamic acid 2-(3-methylphenoxy)ethyl ester 
• 60345-97-3 3-(2-hydroxyethoxy)benzaldehyde 
• 108-39-4 3-methyl-phenol 
• 6807-10-9 2-(m-tolyloxy)ethyl acetate 
• 176851-48-2 2-(3-methylphenoxy)acetaldehyde 
• 319494-43-4 4-(4-hydroxy-2-methyl-phenyl)-4-oxo-butyric acid 
• 107150-67-4 5-[4-(2-hydroxy-ethoxy)-2-methyl-phenyl]-dihydro-furan-2-one 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of a series of alkoxy-3-indolylacetic acids as peroxisome proliferator-activated receptor γ/δ agonists We dedicate this article to Professor Young-Ger Suh on the occasion of his retirement.

Abstract A series of alkoxy-3-indolylacetic acid analogs has been discovered as peroxisome proliferator-activated receptor (PPAR) agonists. Structure-activity relationship study indicated that PPARα/γ/δ activities were dependent on the nature of the hydrophobic group, the attachment position of the alkoxy linker to the indole ring, and N-alkylation of indole nitrogen. Some compounds presented significant PPARγ/δ activity and molecular modeling suggested their putative binding modes in the ligand binding domain of PPARγ. Of these, compound 51 was selected for in vivo study via an evaluation of microsomal stability in mouse and human liver. Compound 51 lowered the levels of fasting blood glucose, insulin, and HbA1c without gain in body weight in db/db mice. When compound 51 was treated, hepatic triglycerides level and the size of adipocytes in white adipose tissue of db/db mice were also reduced as opposed to treatment with rosiglitazone. Taken together, compound 51 shows high potential warranting further studies in models for diabetes and related metabolic disorders and may be in use as a chemical tool for the understanding of PPAR biology.

SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF

Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.

Borohydride exchange resin: Selective reduction of aliphatic carboxylic acids

The aliphatic carboxylic acids can be reduced selectively to the corresponding alcohol in the presence of aromatic carboxylic acids within 30 min with borohydride exchange resin (BER).

New Oxidative Aromatization of α,β-Unsaturated Cyclohexenones with Iodine-Cerium(IV) Ammonium Nitrate in Alcohol

The reaction of 2-cyclohexen-1-one derivatives with iodine-cerium(IV) ammonium nitrate in alcohols (methanol, ethanol, 1-propanol, 2-propanol, and 1-butanol) under refluxing, gave the corresponding alkyl phenyl ethers in good yields.In the case of diol (ethylene glycol, 1,3-propanediol, and 1,4-butanediol), phenoxyalkanol derivatives were obtained.The present method was also applicable to oxidative rearrangement of isophorone.

Dye mixtures of anthraquinone dyes

Dye mixtures containing at least two dyes of the formula (1) STR1 wherein R is hydrogen, methyl or ethyl, and n is an integer from 2 to 4, exhibit on synthetic textile material a build-up which is considerably better than that of the individual dyes.